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Product details

alpha 1 Catenin Recombinant Rabbit Monoclonal Antibody [SC0619]

Catalog number ET1610-46

Price for ET1610-46

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Size / count 100 µL

About this product

α E-catenin (also designated α-catenin; cadherin-associated protein, α1, 102 kDa; and CAP102) plays a role in E-cadherin mediated cell-cell adhesion by linking E-cadherin to the cytoskeleton via β- or γ-catenin and Actin. α E-catenin connects cell-density-dependent adherens junctions with the developmental hedgehog pathway and may provide a negative feedback loop controlling the size of developing cerebral cortex. It is abundant in neuroepithelial precursor cells in the developing cortical ventricular zone of the brain, with reduced expression in the cortical plate. α E-catenin-vinculin interactions play a role in the assembly of the apical junction complex in epithelia. Catenins generally are thought to work as connectors that anchor E-cadherin to the cytoskeletal Actin bundle through the cadherin cytoplasmic domain. Dysfunction of this adhesion complex causes dissociation of cancer cells from primary tumor nodules, thus possibly contributing to cancer invasion and metastasis.

Specifications

Catalog number
ET1610-46
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Alpha E-catenin antibody Cadherin associated protein 102kDa antibody Cadherin associated protein antibody Cadherin-associated protein antibody CAP 102 antibody CAP102 antibody Catenin (cadherin associated protein) alpha 1 102kDa antibody Catenin (cadherin associated protein), alpha 1, 102kDa antibody Catenin alpha 1 antibody Catenin alpha-1 antibody CTNA1_HUMAN antibody CTNNA 1 antibody Ctnna1 antibody FLJ36832 antibody FLJ52416 antibody NY REN 13 antigen antibody OTTHUMP00000224141 antibody OTTHUMP00000224147 antibody Renal carcinoma antigen NY REN 13 antibody Renal carcinoma antigen NY-REN-13 antibody
Abbreviation
CTNNA1
Swiss Prot
P35221 Human, P26231 Mouse,
Cellular Locus
Cytoplasm, Cell junction, Cell membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human alpha 1 Catenin aa 1-90 / 906.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
Positive Control
Hela cell lysate, HepG2 cell lysate, A431 cell lysate, mouse colon tissue, mouse prostate tissue, mouse uterus tissue, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
100 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for alpha 1 Catenin Recombinant Rabbit Monoclonal Antibody [SC0619]?

The catalog number for alpha 1 Catenin Recombinant Rabbit Monoclonal Antibody [SC0619] is ET1610-46.

What sizes are available for alpha 1 Catenin Recombinant Rabbit Monoclonal Antibody [SC0619]?

alpha 1 Catenin Recombinant Rabbit Monoclonal Antibody [SC0619] is available in the following size(s): 100 µL.

Is alpha 1 Catenin Recombinant Rabbit Monoclonal Antibody [SC0619] in stock?

alpha 1 Catenin Recombinant Rabbit Monoclonal Antibody [SC0619] is currently made to order / not held in immediate stock. Contact us for lead time.

What is alpha 1 Catenin Recombinant Rabbit Monoclonal Antibody [SC0619] used for?

α E-catenin (also designated α-catenin; cadherin-associated protein, α1, 102 kDa; and CAP102) plays a role in E-cadherin mediated cell-cell adhesion by linking E-cadherin to the cytoskeleton via β- or γ-catenin and Actin. α E-catenin connects cell-density-dependent adherens junctions with the develo

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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