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![eIF5A Recombinant Rabbit Monoclonal Antibody [SC60-09] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8d061270361ea81eb8/imageurl/et1610-49.webp)
Product details
Catalog number ET1610-49
Price for ET1610-49
Size / count 100 µL
In mammalian cells, translation is controlled at the level of polypeptide chain initiation by eukaryotic initiation factors. The human eukaryotic translation initiation factor 5A gene, also designated eIF-4D or eIF5A, maps to chromosome 17p13.1 and encodes a 154 amino acid protein that is linked to cellular polyamine homeostasis. eIF5A localizes to the nuclear and cytoplasmic compartments of mammalian cells where it can stimulate ribosomal peptidyl-transferase and may be involved in nucleocytoplasmic mRNA transport and/or protein translation. eIF5A contains a unique spermidine-derived post-translational modification at Lys-50, hypusine, which is necessary for eIF5A's biochemical activity and for cellular proliferative signaling. In addition, eIF5A is a cellular cofactor for the function of the Rev transactivator protein of human immunodeficiency virus type 1 (HIV-1). Inhibition of eIF5A interaction with Rev leads to a block of the viral replication cycle.
The catalog number for eIF5A Recombinant Rabbit Monoclonal Antibody [SC60-09] is ET1610-49.
eIF5A Recombinant Rabbit Monoclonal Antibody [SC60-09] is available in the following size(s): 100 µL.
eIF5A Recombinant Rabbit Monoclonal Antibody [SC60-09] is currently made to order / not held in immediate stock. Contact us for lead time.
In mammalian cells, translation is controlled at the level of polypeptide chain initiation by eukaryotic initiation factors. The human eukaryotic translation initiation factor 5A gene, also designated eIF-4D or eIF5A, maps to chromosome 17p13.1 and encodes a 154 amino acid protein that is linked to
Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.
Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.
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