HDAC3 Recombinant Rabbit Monoclonal Antibody [SC55-02] — image 1 of 3

Product details

HDAC3 Recombinant Rabbit Monoclonal Antibody [SC55-02]

Catalog number ET1610-5

Price for ET1610-5

Size / count 100 µL

About this product

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3, all of which are related to the yeast transcriptional factor Rpd3p, have been identified as histone deacetylases.

Specifications

Catalog number: ET1610-5
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: HD3 antibody HDAC 3 antibody HDAC3 antibody HDAC3_HUMAN antibody Histone deacetylase 3 antibody RPD3 2 antibody RPD3 antibody RPD3-2 antibody SMAP45 antibody
Abbreviation: HD3, HDAC3
Swiss Prot: O15379 Human, O88895 Mouse, Q6P6W3 Rat
Cellular Locus: Cytoplasm, Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within C-terminal human HDAC3.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P, IP
Positive Control: HeLa cell lysate, K-562 cell lysate, HEK-293 cell lysate, HT-29 cell lysate, NIH/3T3 cell lysate, C6 cell lysate, COS-1 cell lysate, HeLa, human skin tissue, mouse skin tissue, rat skin tissue, human tonsil tissue, human breast carcinoma tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000 ;IF-Cell: 1:50 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:200-1:1,000 ;IP: Use at an assay dependent concentration.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 49 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for HDAC3 Recombinant Rabbit Monoclonal Antibody [SC55-02]?

The catalog number for HDAC3 Recombinant Rabbit Monoclonal Antibody [SC55-02] is ET1610-5.

What sizes are available for HDAC3 Recombinant Rabbit Monoclonal Antibody [SC55-02]?

HDAC3 Recombinant Rabbit Monoclonal Antibody [SC55-02] is available in the following size(s): 100 µL.

Is HDAC3 Recombinant Rabbit Monoclonal Antibody [SC55-02] in stock?

HDAC3 Recombinant Rabbit Monoclonal Antibody [SC55-02] is currently made to order / not held in immediate stock. Contact us for lead time.

What is HDAC3 Recombinant Rabbit Monoclonal Antibody [SC55-02] used for?

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.