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Product details

Sonic Hedgehog Protein/SHH (C-Product) Recombinant Rabbit Monoclonal Antibody [SC05-28]

Catalog number ET1610-6

Price for ET1610-6

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Size / count 100 µL

About this product

The Drosophila segment polarity gene hedgehog (hh) encodes a precursor protein which undergoes autocleavage to generate amino- and carboxy-terminal peptides. Both proteins are secreted and appear to function in embryonic and imaginal disc patterning. Several vertebrate homologs of Drosophila hh have been identified. These include Sonic hedgehog (Shh) (alternatively designated Vhh-1), Desert hedgehog (Dhh) and Indian hedgehog (Ihh). Each contain amino-terminal signal peptides and apparently function as secreted proteins involved in the mediation of various cell-cell interactions. Shh resembles Drosophila hh in that it is processed to generate an amino-terminal secreted peptide that is retained at or near the cell surface and a carboxy-terminal glycosylated more diffusible peptide.

Specifications

Catalog number
ET1610-6
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
HHG 1 antibody HHG-1 antibody HHG1 antibody HLP 3 antibody HLP3 antibody Holoprosencephaly 3 antibody HPE 3 antibody HPE3 antibody MCOPCB5 antibody shh antibody SHH_HUMAN antibody SMMC I antibody SMMCI antibody Sonic Hedgehog (Drosophila) homolog antibody sonic hedgehog homolog (Drosophila) antibody Sonic hedgehog homolog antibody Sonic hedgehog protein antibody Sonic hedgehog protein C-product antibody TPT antibody TPTPS antibody
Abbreviation
SHH
Swiss Prot
Q15465 Human, Q62226 Mouse
Cellular Locus
Secreted, Cell membrane.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within Human Sonic Hedgehog Protein aa 258-307 / 462.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, FC
Positive Control
Mouse kidney tissue lysate, mouse brain tissue lysate, mouse liver tissue lysate, H22 cell lysate, Neuro-2a cell lysate, NIH/3T3 cell lysate, Neuro-2a, Hela, A549, 293, human liver cancer tissue, rat kidney tissue, rat liver tissue, human liver tissue, mouse liver tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:200-1:1,000 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 50 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Sonic Hedgehog Protein/SHH (C-Product) Recombinant Rabbit Monoclonal Antibody [SC05-28]?

The catalog number for Sonic Hedgehog Protein/SHH (C-Product) Recombinant Rabbit Monoclonal Antibody [SC05-28] is ET1610-6.

What sizes are available for Sonic Hedgehog Protein/SHH (C-Product) Recombinant Rabbit Monoclonal Antibody [SC05-28]?

Sonic Hedgehog Protein/SHH (C-Product) Recombinant Rabbit Monoclonal Antibody [SC05-28] is available in the following size(s): 100 µL.

Is Sonic Hedgehog Protein/SHH (C-Product) Recombinant Rabbit Monoclonal Antibody [SC05-28] in stock?

Sonic Hedgehog Protein/SHH (C-Product) Recombinant Rabbit Monoclonal Antibody [SC05-28] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Sonic Hedgehog Protein/SHH (C-Product) Recombinant Rabbit Monoclonal Antibody [SC05-28] used for?

The Drosophila segment polarity gene hedgehog (hh) encodes a precursor protein which undergoes autocleavage to generate amino- and carboxy-terminal peptides. Both proteins are secreted and appear to function in embryonic and imaginal disc patterning. Several vertebrate homologs of Drosophila hh have

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

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