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Product details

CD21 Recombinant Rabbit Monoclonal Antibody [SC0681]

Catalog number ET1610-61

Price for ET1610-61

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Size / count 100 µL

About this product

CD21 is a type I integral membrane glycoprotein that serves as a receptor for the C3d complement fragment and for the Epstein-Barr virus. It plays a role in B cell activation and proliferation and undergoes phosphorylation after B cell activation with phorbol esters. CD21 is expressed on mature B cells, follicular dendritic cells, pharyngeal and cervical epithelial cells and a subset of thymocytes. The adaptive immune response is tightly regulated to limit responding cells in an antigen-specific manner. On B cells, co-receptors CD21/CD19 modulate the strength of B cell Ag receptor (BCR) signals, thereby influencing cell fate. Complement receptor (CR) type 2 (CR2/ CD21) is normally expressed during the immature and mature stages of B cell development. In association with CD19, CR21 plays an important role in enhancing mature B cell responses to foreign antigens.

Specifications

Catalog number
ET1610-61
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
C3DR antibody CD 21 antibody CD21 antibody Complement C3d receptor antibody Complement component (3d/Epstein Barr virus) receptor 2 antibody Complement receptor type 2 antibody CR antibody Cr2 antibody CR2_HUMAN antibody CVID7 antibody EBV receptor antibody EBV-R antibody Epstein Barr virus receptor antibody Epstein-Barr virus receptor antibody EVBR antibody SLEB9 antibody
Abbreviation
Cr2, EBV receptor, CR2
Swiss Prot
P20023 Human, P19070 Mouse
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human CD21 aa 989-1033 / 1033.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, IP, FC, IF-Tissue
Positive Control
Raji cell lysate, HepG2, A549, human tonsil tissue, human spleen tissue, human lymph nodes tissue.
Concentration
1 mg/mL
Dilution
WB: 1:5,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:800 ;IP: Use at an assay dependent concentration. ;FC: 1;1,000 ;IF-Tissue: 1:50-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 113 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for CD21 Recombinant Rabbit Monoclonal Antibody [SC0681]?

The catalog number for CD21 Recombinant Rabbit Monoclonal Antibody [SC0681] is ET1610-61.

What sizes are available for CD21 Recombinant Rabbit Monoclonal Antibody [SC0681]?

CD21 Recombinant Rabbit Monoclonal Antibody [SC0681] is available in the following size(s): 100 µL.

Is CD21 Recombinant Rabbit Monoclonal Antibody [SC0681] in stock?

CD21 Recombinant Rabbit Monoclonal Antibody [SC0681] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD21 Recombinant Rabbit Monoclonal Antibody [SC0681] used for?

CD21 is a type I integral membrane glycoprotein that serves as a receptor for the C3d complement fragment and for the Epstein-Barr virus. It plays a role in B cell activation and proliferation and undergoes phosphorylation after B cell activation with phorbol esters. CD21 is expressed on mature B ce

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

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