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Product details

Mast Cell Tryptase Recombinant Rabbit Monoclonal Antibody [SC68-07]

Catalog number ET1610-64

Price for ET1610-64

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Size / count 100 µL

About this product

Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Mast cell chymase, known as CMA1, is a major secreted serine protease that is involved in vasoactive peptide generation, extracellular matrix degradation and regulation of gland secretion. The human chymase gene, which maps to human chromosome 14q11.2, encodes a preproenzyme with a 19-amino acid signal peptide, an acidic 2-amino acid propeptide and a 226-amino acid catalytic domain. Tryptases comprise a family of trypsin-like serine proteases that are enzymatically active as heparin-stabilized tetramers. There are four functional genes for tryptase: α I, β I, β II and γ I, which map to human chromosome 16p13.3, with β tryptases representing the main isoenzymes expressed in mast cells. Mast cell proteases are a family of rodent protein homologs to human tryptases that are specifically expressed in mast cells and may serve as highly specific markers in the analysis of mast cell heterogeneity, differentiation and function.

Specifications

Catalog number
ET1610-64
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
alpha II antibody Lung tryptase antibody Mast cell alpha II tryptase antibody Mast cell beta I tryptase antibody Mast cell protease 7 antibody Mast cell protease II antibody MCP 7 antibody Pituitary tryptase antibody Skin tryptase antibody TPS 1 antibody TPS1 antibody TPS2 antibody TPSAB1 antibody TPSAB1 protein antibody TPSB1 antibody Tryptase 1 antibody Tryptase alpha 1 antibody tryptase alpha I included antibody Tryptase alpha II antibody tryptase alpha II included antibody tryptase alpha included antibody tryptase alpha/beta 1 antibody Tryptase beta 1 antibody tryptase beta I included antibody Tryptase I antibody tryptase I included antibody Tryptase III antibody Tryptase skin antibody
Abbreviation
Tryptase-1, TPSAB1
Swiss Prot
Q15661 Human, Q02844 Mouse
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant protein within Human Mast Cell Tryptase aa 10-275 / 275.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IP, mIHC
Positive Control
Human lung tissue lysates, mouse skin tissue lysates, human lung tissue, human tonsil tissue, human small intestine tissue, human prostate carcinoma tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:5,000-1:10,000 ;IP: Use at an assay dependent concentration. ;mIHC: 1:3,000-1:5,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 30 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Mast Cell Tryptase Recombinant Rabbit Monoclonal Antibody [SC68-07]?

The catalog number for Mast Cell Tryptase Recombinant Rabbit Monoclonal Antibody [SC68-07] is ET1610-64.

What sizes are available for Mast Cell Tryptase Recombinant Rabbit Monoclonal Antibody [SC68-07]?

Mast Cell Tryptase Recombinant Rabbit Monoclonal Antibody [SC68-07] is available in the following size(s): 100 µL.

Is Mast Cell Tryptase Recombinant Rabbit Monoclonal Antibody [SC68-07] in stock?

Mast Cell Tryptase Recombinant Rabbit Monoclonal Antibody [SC68-07] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Mast Cell Tryptase Recombinant Rabbit Monoclonal Antibody [SC68-07] used for?

Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Mast cell chymase, known as CMA1, is a major secreted serine protease that is involved in vasoactive peptide generation, extrace

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

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