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Product details

GARS Recombinant Rabbit Monoclonal Antibody [SC0651]

Catalog number ET1610-67

Price for ET1610-67

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Size / count 100 µL

About this product

The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases. Proteins belonging to this family function to catalyze the aminoacylation of tRNAs by their corresponding amino acids, thus linking amino acids with tRNA-contained nucleotide triplets. GlyRS (Glycyl-tRNA synthetase), also known as Glycine-tRNA ligase, is a 739 amino acid class II synthetase that is widely expressed, including in the brain and spinal cord. Defects in the gene encoding GlyRS is the cause of Charcot-Marie-Tooth disease type 2D (CMT2D), which is an autosomal dominant inherited disease characterized by severe weakness, atrophy and absence of deep tendon reflexes in the upper extremities. Defects in the GlyRS gene is also the cause of distal hereditary muscular neuropathy type V (HMN5), a disease similar to CMT2D, though the distal sensory involvement is less severe in HMN5 patients.

Specifications

Catalog number
ET1610-67
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
AP 4 A synthetase antibody Charcot Marie Tooth neuropathy 2D antibody Charcot Marie Tooth neuropathy neuronal type D antibody CMT2D antibody Diadenosine tetraphosphate synthetase antibody DSMAV antibody EC 6.1.1.14 antibody Glycine tRNA ligase antibody Glycyl tRNA synthetase antibody GlyRS antibody HMN5 antibody SMAD1 antibody
Abbreviation
AP-4-A synthetase, GlyRS, GARS
Swiss Prot
P41250 Human, Q9CZD3 Mouse, Q5I0G4 Rat
Cellular Locus
Cytoplasm, Mitochondrion, Cell projection.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human GARS aa 698-739 / 739.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Raji cell lysates, mouse colon tissue, mouse heart tissue, human pancreas tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
83 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for GARS Recombinant Rabbit Monoclonal Antibody [SC0651]?

The catalog number for GARS Recombinant Rabbit Monoclonal Antibody [SC0651] is ET1610-67.

What sizes are available for GARS Recombinant Rabbit Monoclonal Antibody [SC0651]?

GARS Recombinant Rabbit Monoclonal Antibody [SC0651] is available in the following size(s): 100 µL.

Is GARS Recombinant Rabbit Monoclonal Antibody [SC0651] in stock?

GARS Recombinant Rabbit Monoclonal Antibody [SC0651] is currently made to order / not held in immediate stock. Contact us for lead time.

What is GARS Recombinant Rabbit Monoclonal Antibody [SC0651] used for?

The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases. Proteins belonging to this family function to catalyze the aminoacylation of tRNAs by their corresponding amino acids, thus linking amino acids with tRNA-contained nucleotide t

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

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