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Product details

PYK2 Recombinant Rabbit Monoclonal Antibody [SC06-15]

Catalog number ET1610-82

Price for ET1610-82

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Size / count 100 µL

About this product

This gene encodes a cytoplasmic protein tyrosine kinase that is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. In addition, SOCE-induced Pyk2 activation mediates disassembly of endothelial adherens junctions, via tyrosine (Y1981-residue) phosphorylation of VE-PTP.

Specifications

Catalog number
ET1610-82
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
CADTK antibody CAK-beta antibody CAKB antibody CAKbeta antibody Calcium regulated non receptor proline rich tyrosine kinase antibody Calcium-dependent tyrosine kinase antibody Cell adhesion kinase beta antibody E430023O05Rik antibody EC 2.7.10.2 antibody FADK 2 antibody FADK2 antibody FAK2 antibody FAK2_HUMAN antibody Focal adhesion kinase 2 antibody MGC124628 antibody PKB antibody Proline-rich tyrosine kinase 2 antibody Protein kinase B antibody Protein Tyrosine Kinase 2 Beta antibody Protein-tyrosine kinase 2-beta antibody PTK antibody PTK2B antibody PTK2B protein tyrosine kinase 2 beta antibody PYK2 antibody RAFTK antibody RAFTK2 antibody Related adhesion focal tyrosine kinase antibody
Abbreviation
CADTK, CAK-beta, CAKB, FADK 2, RAFTK, PTK2B
Swiss Prot
Q14289 Human, Q9QVP9 Mouse, P70600 Rat
Cellular Locus
Cell membrane, Nucleus, Cytoplasm, perinuclear region, focal adhesion, lamellipodium, cell cortex.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within N-terminal human PYK2.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P
Positive Control
A431 cell lysate, Jurkat cell lysate, mouse brain tissue lysate, rat brain tissue lysate, Hela, SHG-44, SH-SY5Y, human tonsil tissue, human spleen tissue, human kidney tissue, mouse brain tissue, mouse kidney tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 116 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for PYK2 Recombinant Rabbit Monoclonal Antibody [SC06-15]?

The catalog number for PYK2 Recombinant Rabbit Monoclonal Antibody [SC06-15] is ET1610-82.

What sizes are available for PYK2 Recombinant Rabbit Monoclonal Antibody [SC06-15]?

PYK2 Recombinant Rabbit Monoclonal Antibody [SC06-15] is available in the following size(s): 100 µL.

Is PYK2 Recombinant Rabbit Monoclonal Antibody [SC06-15] in stock?

PYK2 Recombinant Rabbit Monoclonal Antibody [SC06-15] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PYK2 Recombinant Rabbit Monoclonal Antibody [SC06-15] used for?

This gene encodes a cytoplasmic protein tyrosine kinase that is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitte

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

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