Cortactin Recombinant Rabbit Monoclonal Antibody [SC61-08] — image 1 of 3

Product details

Cortactin Recombinant Rabbit Monoclonal Antibody [SC61-08]

Catalog number ET1610-87

Price for ET1610-87

Size / count 100 µL

About this product

Cortactin (also designated Ems-1) is a filamentous Actin (F-Actin) binding protein that has been shown to be a substrate for Src p60. Cortactin contains tandem 37 amino acid repeats at the amino-terminus and an SH3 domain at the carboxy-terminus. The tandem repeats appear to be necessary for F-Actin binding. Tyrosine phosphorylation of Cortactin by Src p60 results in diminished F-Actin binding to Cortactin and reduced F-Actin cross-linking activity. Cortactin has also been shown to be phosphorylated in response to FGF-1. Cortactin exhibits abundant expression in megakaryocytes and platelets, and it may play a role in the maturation of megakaryocytes.

Specifications

Catalog number: ET1610-87
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Amplaxin antibody CTTN antibody EMS 1 antibody EMS1 antibody FLJ34459 antibody Mammary tumor and squamous cell carcinoma associated antibody Oncogene EMS1 antibody p80/85 src substrate antibody Src substrate cortactin antibody SRC8_HUMAN antibody
Abbreviation: CTTN
Swiss Prot: Q14247 Human, Q60598 Mouse
Cellular Locus: Cytoplasm, Cell projection, Membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human Cortactin aa 34-67 / 550.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
Positive Control: Hela cell lysate, NIH/3T3 cell lysate, HeLa, human tonsil tissue, mouse colon tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:2,000 ;IF-Cell: 1:100 ;IF-Tissue: 1:100-1:500 ;IHC-P: 1:200-1:1,000 ;FC: 1:1,000 ;IP: Use at an assay dependent concentration.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 62 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Cortactin Recombinant Rabbit Monoclonal Antibody [SC61-08]?

The catalog number for Cortactin Recombinant Rabbit Monoclonal Antibody [SC61-08] is ET1610-87.

What sizes are available for Cortactin Recombinant Rabbit Monoclonal Antibody [SC61-08]?

Cortactin Recombinant Rabbit Monoclonal Antibody [SC61-08] is available in the following size(s): 100 µL.

Is Cortactin Recombinant Rabbit Monoclonal Antibody [SC61-08] in stock?

Cortactin Recombinant Rabbit Monoclonal Antibody [SC61-08] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cortactin Recombinant Rabbit Monoclonal Antibody [SC61-08] used for?

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.