RALBP1 Recombinant Rabbit Monoclonal Antibody [SC06-49]

About this product

Ral A and Ral B constitute a distinct subfamily of Ras-related GTPases (i.e., GDP/GTP binding proteins). Ral proteins are activated by a unique nucleotide exchange factor, Ral GDS, and deactivated by a distinct GTPase-activating protein. Unlike Ras proteins, Ral A and Ral B fail to induce transformed foci when activated variants are expressed in various recipient cells. A potential downstream target of Ral, designated Ral BP-1, has been shown to contain a Rho-GTPase-activating domain. This Rho-GTPase-activating domain interacts preferentially with the Rho family member Cdc42. A Ras/Ral signaling pathway has been reported to mediate phospholipase D (PLD) activation by v-Src, thus indicating PLD as another downstream target of Ral A.

Specifications

Catalog number

ET1610-88

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

RLIP1 antibody 76 kDa Ral-interacting protein antibody 76-kDa Ral-interacting protein antibody Dinitrophenyl S-glutathione ATPase antibody DNP-SG ATPase antibody Ral-interacting protein 1 antibody Ral-interacting protein 1, 76-KD antibody RalA-binding protein 1 antibody RalBP1 antibody RBP1_HUMAN antibody RIP1 antibody RLIP1 antibody RLIP76 antibody

Abbreviation

DNP-SG ATPase, RALBP1

Swiss Prot

Q15311 Human, Q62172 Mouse, Q62796 Rat

Cellular Locus

Membrane.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within Human RALBP1 aa 205-300 / 655.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, FC

Positive Control

HCT116 cell lysate, Jurkat cell lysate, 293T cell lysate, human breast carcinoma tissue, human pancreas tissue, mouse lung tissue, mouse testis tissue, mouse pancreas tissue, 293.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:5,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 76 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes