IRF7 Recombinant Rabbit Monoclonal Antibody [SC0617] — image 1 of 3

Product details

IRF7 Recombinant Rabbit Monoclonal Antibody [SC0617]

Catalog number ET1610-89

Discontinued

Price for ET1610-89

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including the type I interferon genes. In particular, IRF7 regulates many interferon-alpha genes. Constitutive expression of IRF7 is largely restricted to lymphoid tissue, largely plasmacytoid dendritic cells, whereas IRF7 is inducible in many tissues. The IRF7 pathway was shown to be silenced in some metastatic breast cancer cell lines, which may help the cells avoid the host immune response. Restoring IRF7 to these cell lines reduced metastases and increased host survival time in animal models. The IRF7 gene and product were shown to be defective in a patient with severe susceptibility to H1N1 influenza, while susceptibility to other viral diseases such as CMV, RSV, and parainfluenza was unaffected.

Specifications

Catalog number: ET1610-89
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
CAS Number: 9000-83-3
Product Name Alternative: IMD39 antibody Interferon regulatory factor 7 antibody Interferon regulatory factor 7H antibody IRF 7 antibody IRF 7A antibody IRF 7H antibody IRF-7 antibody IRF7 antibody IRF7_HUMAN antibody IRF7A antibody IRF7B antibody IRF7C antibody IRF7H antibody
Abbreviation: IRF-7, IRF7
Swiss Prot: Q92985 Human, P70434 Mouse
Cellular Locus: Nucleus, Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat, Zebrafish
Immunogen: Synthetic peptide within human IRF7 aa 200-240.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC, IP
Positive Control: Jurkat cell lysate, Raji cell lysate, hybrid fish (crucian-carp) brain tissue lysates, PC-12, HepG2, 293, human tonsil tissue, human spleen tissue, human kidney tissue, mouse liver tissue, mouse kidney tissue, mouse heart tissue, Raji.
Concentration: 1 mg/mL
Dilution: WB: 1:2,000-1:5,000 ;IF-Cell: 1:100-1:500 ;IF-Tissue: 1:100-1:500 ;IHC-P: 1:50-1:200 ;FC: 1:100 ;IP: Use at an assay dependent concentration.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 54 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for IRF7 Recombinant Rabbit Monoclonal Antibody [SC0617]?

The catalog number for IRF7 Recombinant Rabbit Monoclonal Antibody [SC0617] is ET1610-89.

Is IRF7 Recombinant Rabbit Monoclonal Antibody [SC0617] in stock?

IRF7 Recombinant Rabbit Monoclonal Antibody [SC0617] is currently made to order / not held in immediate stock. Contact us for lead time.

What is IRF7 Recombinant Rabbit Monoclonal Antibody [SC0617] used for?

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.