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Product details

C/EBP Beta Recombinant Rabbit Monoclonal Antibody [SC55-05]

Catalog number ET1610-9

Discontinued

Price for ET1610-9

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Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

The protein encoded by this intronless gene is a bZIP transcription factor that can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. CEBP-beta is critical for normal macrophage functioning, an important immune cell sub-type; mice unable to express CEBP-beta have macrophages that cannot differentiate (specialize) and thus are unable to perform all their biological functions - including macrophage-mediated muscle repair. Observational work has shown that expression of CEBP-beta in blood leukocytes is positively associated with muscle strength in humans, emphasizing the importance of the immune system, and particularly macrophages, in the maintenance of muscle function. Function of CEBPB gene can be effectively examined by siRNA knockdown based on an independent validation.

Specifications

Catalog number
ET1610-9
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
CAS Number
9000-83-3
Product Name Alternative
AGP/EBP antibody C EBP beta antibody C/EBP beta antibody C/EBP related protein 2 antibody CCAAT Enhancer Binding Protein beta antibody CCAAT/enhancer-binding protein beta antibody CEBPB antibody CEBPB_HUMAN antibody CRP2 antibody IL 6DBP antibody IL6DBP antibody Interleukin 6 dependent binding protein antibody LAP antibody Liver activator protein antibody Liver enriched transcriptional activator antibody NF IL6 antibody NFIL6 antibody Nuclear factor NF IL6 antibody Nuclear factor NF-IL6 antibody SF B antibody SFB antibody Silencer factor B antibody TCF-5 antibody TCF5 antibody Transcription factor 5 antibody
Abbreviation
C/EBP beta, LAP, LIP, TCF-5, CEBPB, TCF5
Swiss Prot
P17676 Human, P28033 Mouse, P21272 Rat
Cellular Locus
Cytoplasm, Nucleus.
Host
Rabbit
Species Reactivity
Human, Rat, Mouse
Immunogen
Synthetic peptide within Rat C/EBP Beta aa 248-297 / 297.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, FC, IP
Positive Control
PC-12 cell lysates, Hela, MCF-7, PC-12.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 36 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for C/EBP Beta Recombinant Rabbit Monoclonal Antibody [SC55-05]?

The catalog number for C/EBP Beta Recombinant Rabbit Monoclonal Antibody [SC55-05] is ET1610-9.

Is C/EBP Beta Recombinant Rabbit Monoclonal Antibody [SC55-05] in stock?

C/EBP Beta Recombinant Rabbit Monoclonal Antibody [SC55-05] is currently made to order / not held in immediate stock. Contact us for lead time.

What is C/EBP Beta Recombinant Rabbit Monoclonal Antibody [SC55-05] used for?

The protein encoded by this intronless gene is a bZIP transcription factor that can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes invol

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

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