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Product details

NQO2 Recombinant Rabbit Monoclonal Antibody [SC06-68]

Catalog number ET1610-92

Price for ET1610-92

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Size / count 100 µL

About this product

NAD (P)H dehydrogenase, quinone 2, also known as QR2, is a protein that in humans is encoded by the NQO2 gene. It is a phase II detoxification enzyme which can carry out two or four electron reductions of quinones. Its mechanism of reduction is through a ping-pong mechanism involving its FAD cofactor. Initially in a reductive phase NQO2 binds to reduced dihydronicotinamide riboside (NRH) electron donor, and mediates a hydride transfer from NRH to FAD. Then, in an oxidative phase, NQO2 binds to its quinone substrate and reduces the quinone to a dihydroquinone. Besides the two catalytic FAD, NQO2 also has two zinc ions. It is not clear whether the metal has a catalytic role. NQO2 is a homodimer. NQO2 can be inhibited by resveratrol. One of QR2's binding sites responds to 2-iodomelatonin, and has been referred to as MT3.

Specifications

Catalog number
ET1610-92
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
DHQV antibody DIA6 antibody EC 1.10.99.2 antibody MGC94180 antibody NAD (P)H dehydrogenase quinone 2 antibody NAD (P)H menadione oxidoreductase 1 dioxin inducible 2 antibody NAD (P)H menadione oxidoreductase 2 dioxin inducible antibody NMOR2 antibody NQO 2 antibody NQO2 antibody NQO2_HUMAN antibody NRH dehydrogenase [quinone] 2 antibody NRH dehydrogenase antibody NRH:quinone oxidoreductase 2 antibody OTTHUMP00000015948 antibody OTTHUMP00000015949 antibody OTTHUMP00000015953 antibody Ox 2 antibody Ox2 antibody QR2 antibody Quinone antibody Quinone reductase 2 antibody Ribosyldihydronicotinamide dehydrogenase [quinone] antibody Ribosyldihydronicotinamide dehydrogenase antibody
Abbreviation
QR2, NQO2
Swiss Prot
P16083 Human, Q9JI75 Mouse, Q6AY80 Rat
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human NQO2 aa 2-49 / 231.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Hela cell lysates, human kidney tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 26 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for NQO2 Recombinant Rabbit Monoclonal Antibody [SC06-68]?

The catalog number for NQO2 Recombinant Rabbit Monoclonal Antibody [SC06-68] is ET1610-92.

What sizes are available for NQO2 Recombinant Rabbit Monoclonal Antibody [SC06-68]?

NQO2 Recombinant Rabbit Monoclonal Antibody [SC06-68] is available in the following size(s): 100 µL.

Is NQO2 Recombinant Rabbit Monoclonal Antibody [SC06-68] in stock?

NQO2 Recombinant Rabbit Monoclonal Antibody [SC06-68] is currently made to order / not held in immediate stock. Contact us for lead time.

What is NQO2 Recombinant Rabbit Monoclonal Antibody [SC06-68] used for?

NAD (P)H dehydrogenase, quinone 2, also known as QR2, is a protein that in humans is encoded by the NQO2 gene. It is a phase II detoxification enzyme which can carry out two or four electron reductions of quinones. Its mechanism of reduction is through a ping-pong mechanism involving its FAD cofacto

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

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