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Product details

IKB beta Recombinant Rabbit Monoclonal Antibody [SN0648]

Catalog number ET1611-1

Price for ET1611-1

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Size / count 100 µL

About this product

NF-kappa-B inhibitor beta is a protein that in humans is encoded by the NFKBIB gene. NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).

Specifications

Catalog number
ET1611-1
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
I kappa B beta antibody I-kappa-B-beta antibody IkappaBbeta antibody IKB beta antibody IkB-B antibody IkB-beta antibody IKBB antibody IKBB_HUMAN antibody IkBbeta antibody NF kappa BIB antibody NF-kappa-B inhibitor beta antibody NF-kappa-BIB antibody Nfkbib antibody Thyroid receptor interacting protein 9 antibody Thyroid receptor-interacting protein 9 antibody TR interacting protein 9 antibody TR-interacting protein 9 antibody TRIP-9 antibody TRIP9 antibody
Abbreviation
NF-kappa-BIB, IkB-B, IkB-beta, IkappaBbeta, TR-interacting protein 9, TRIP-9, NFKBIB
Swiss Prot
Q15653 Human
Cellular Locus
Nucleus, Cytoplasm.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human IKB beta aa 322-356 / 356.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, IP
Positive Control
Hela cell lysate, Jurkat cell lysate, A549, MCF-7, human breast carcinoma tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;IP: Use at an assay dependent concentration.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 38 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for IKB beta Recombinant Rabbit Monoclonal Antibody [SN0648]?

The catalog number for IKB beta Recombinant Rabbit Monoclonal Antibody [SN0648] is ET1611-1.

What sizes are available for IKB beta Recombinant Rabbit Monoclonal Antibody [SN0648]?

IKB beta Recombinant Rabbit Monoclonal Antibody [SN0648] is available in the following size(s): 100 µL.

Is IKB beta Recombinant Rabbit Monoclonal Antibody [SN0648] in stock?

IKB beta Recombinant Rabbit Monoclonal Antibody [SN0648] is currently made to order / not held in immediate stock. Contact us for lead time.

What is IKB beta Recombinant Rabbit Monoclonal Antibody [SN0648] used for?

NF-kappa-B inhibitor beta is a protein that in humans is encoded by the NFKBIB gene. NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphoryl

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

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