Product details
Catalog number ET1611-1
Price for ET1611-1
Size / count 100 µL
NF-kappa-B inhibitor beta is a protein that in humans is encoded by the NFKBIB gene. NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).
The catalog number for IKB beta Recombinant Rabbit Monoclonal Antibody [SN0648] is ET1611-1.
IKB beta Recombinant Rabbit Monoclonal Antibody [SN0648] is available in the following size(s): 100 µL.
IKB beta Recombinant Rabbit Monoclonal Antibody [SN0648] is currently made to order / not held in immediate stock. Contact us for lead time.
NF-kappa-B inhibitor beta is a protein that in humans is encoded by the NFKBIB gene. NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphoryl
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