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Product details

Tyrosine Hydroxylase Recombinant Rabbit Monoclonal Antibody [SN59-03]

Catalog number ET1611-12

Price for ET1611-12

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Size / count 100 µL

About this product

Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA). It does so using molecular oxygen (O2), as well as iron (Fe2+) and tetrahydrobiopterin as cofactors. L-DOPA is a precursor for dopamine, which, in turn, is a precursor for the important neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline). Tyrosine hydroxylase catalyzes the rate limiting step in this synthesis of catecholamines. In humans, tyrosine hydroxylase is encoded by the TH gene, and the enzyme is present in the central nervous system (CNS), peripheral sympathetic neurons and the adrenal medulla. Tyrosine hydroxylase, phenylalanine hydroxylase and tryptophan hydroxylase together make up the family of aromatic amino acid hydroxylases (AAAHs).

Specifications

Catalog number
ET1611-12
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Dystonia 14 antibody DYT14 antibody DYT5b antibody EC 1.14.16.2 antibody OTTHUMP00000011225 antibody OTTHUMP00000011226 antibody ple antibody Protein Pale antibody TH antibody The antibody TY3H_HUMAN antibody TYH antibody Tyrosine 3 hydroxylase antibody Tyrosine 3 monooxygenase antibody Tyrosine 3-hydroxylase antibody Tyrosine 3-monooxygenase antibody Tyrosine hydroxylase antibody
Abbreviation
TH
Swiss Prot
P07101 Human, P24529 Mouse, P04177 Rat
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within C-terminal human Tyrosine Hydroxylase.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC, IF-Tissue, mIHC, IHC-Fr
Positive Control
Rat brain tissue lysates, PC-12 cell lysates, N2A, NIH/3T3, SH-SY5Y, mouse brain tissue, rat brain tissue, HEK-293.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:10,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:2,000 ;IHC-Fr: 1:1,000 ;FC: 1:1,000 ;IF-Tissue: 1:200 ;mIHC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 59 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Tyrosine Hydroxylase Recombinant Rabbit Monoclonal Antibody [SN59-03]?

The catalog number for Tyrosine Hydroxylase Recombinant Rabbit Monoclonal Antibody [SN59-03] is ET1611-12.

What sizes are available for Tyrosine Hydroxylase Recombinant Rabbit Monoclonal Antibody [SN59-03]?

Tyrosine Hydroxylase Recombinant Rabbit Monoclonal Antibody [SN59-03] is available in the following size(s): 100 µL.

Is Tyrosine Hydroxylase Recombinant Rabbit Monoclonal Antibody [SN59-03] in stock?

Tyrosine Hydroxylase Recombinant Rabbit Monoclonal Antibody [SN59-03] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Tyrosine Hydroxylase Recombinant Rabbit Monoclonal Antibody [SN59-03] used for?

Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA). It does so using molecular oxygen (O2), as well as iron (Fe2+) and tetrahydrobiopterin as cofactors. L-DOPA is a precursor f

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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