Myosin Light Chain 2 Recombinant Rabbit Monoclonal Antibody [SN67-09]

About this product

Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) also known as the regulatory light chain of myosin (RLC) is a protein that in humans is encoded by the MYL2 gene. This cardiac ventricular RLC isoform is distinct from that expressed in skeletal muscle (MYLPF), smooth muscle (MYL12B) and cardiac atrial muscle (MYL7). Ventricular myosin light chain-2 (MLC-2v) refers to the ventricular cardiac muscle form of myosin light chain 2 (Myl2). MLC-2v is a 19-KDa protein composed of 166 amino acids, that belongs to the EF-hand Ca2+ binding superfamily.[8] MLC-2v interacts with the neck/tail region of the muscle thick filament protein myosin to regulate myosin motility and function.

Specifications

Catalog number

ET1611-13

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Cardiac myosin light chain-2 antibody Cardiac ventricular myosin light chain 2 antibody CMH10 antibody MLC 2v antibody MLC-2 antibody MLC-2v antibody MLC2 antibody MLRV_HUMAN antibody MYL 2 antibody MYL2 antibody Myosin light chain 2 regulatory cardiac slow antibody Myosin light polypeptide 2 regulatory cardiac slow antibody Myosin regulatory light chain 2 antibody Myosin regulatory light chain 2 ventricular/cardiac muscle isoform antibody Regulatory light chain of myosin antibody RLC of myosin antibody Slow cardiac myosin regulatory light chain 2 antibody ventricular/cardiac muscle isoform antibody

Abbreviation

MLC-2, MLC-2v, MLC-2s/v, MYL2

Swiss Prot

P10916 Human, P51667 Mouse, P08733 Rat

Cellular Locus

Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Zebrafish

Immunogen

Synthetic peptide within Human Myosin Light Chain 2 aa 117-166 / 166.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IP

Positive Control

Mouse heart tissue lysate, rat heart tissue lysate, hybrid fish (crucian-carp) skin tissue lysates, human fetal skeletal muscle tissue, rat heart tissue, mouse skeletal muscle tissue, mouse heart tissue, human striated muscle tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:5,000 ;IHC-P: 1:50-1:200 ;IP: Use at an assay dependent concentration.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 19 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes