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![Integrin alpha E Recombinant Rabbit Monoclonal Antibody [SN62-06] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea81933/imageurl/et1611-27.webp)
Product details
Catalog number ET1611-27
Price for ET1611-27
Size / count 100 µL
Integrin, alpha E (ITGAE) also known as CD103 (cluster of differentiation 103) is an integrin protein that in human is encoded by the ITGAE gene. CD103 binds integrin beta 7 (β7– ITGB7) to form the complete heterodimeric integrin molecule αEβ7, which has no distinct name. The αEβ7 complex is often referred to as "CD103" though this strictly refers only to the αE chain. Note that the β7 subunit can bind with other integrin α chains, such as α4 (CD49d). The chief ligand for αEβ7 is E-cadherin, a cellular adhesion molecule (CAM) found on epithelial cells. It is probably important for T cell homing to the intestinal sites and thymocyte contacts with thymic reticuloepithelial cells. Tregs are important for decreasing the immune response and appear to play a crucial role in the prevention of autoimmune diseases. Tregs are defined as CD4+/CD25+/Foxp3+ cells. Some CD4+/FoxP3− cells also express CD103 and have been attributed regulatory activity.
The catalog number for Integrin alpha E Recombinant Rabbit Monoclonal Antibody [SN62-06] is ET1611-27.
Integrin alpha E Recombinant Rabbit Monoclonal Antibody [SN62-06] is available in the following size(s): 100 µL.
Integrin alpha E Recombinant Rabbit Monoclonal Antibody [SN62-06] is currently made to order / not held in immediate stock. Contact us for lead time.
Integrin, alpha E (ITGAE) also known as CD103 (cluster of differentiation 103) is an integrin protein that in human is encoded by the ITGAE gene. CD103 binds integrin beta 7 (β7– ITGB7) to form the complete heterodimeric integrin molecule αEβ7, which has no distinct name. The αEβ7 complex is often r
Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.
Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.
We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.
