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Product details

CXCR7 Recombinant Rabbit Monoclonal Antibody [SN65-09]

Catalog number ET1611-3

Price for ET1611-3

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Size / count 100 µL

About this product

Atypical chemokine receptor 3 also known as C-X-C chemokine receptor type 7 (CXCR-7) and G-protein coupled receptor 159 (GPR159) is a protein that in humans is encoded by the ACKR3 gene. This protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP) and was considered to be an orphan receptor. It is now classified as a chemokine receptor able to bind the chemokines CXCL12/SDF-1 and CXCL11. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. Alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. Whereas some reports claim that the receptor induces signaling following ligand binding, recent findings in zebrafish suggest that CXCR7 functions primarily by sequestering the chemokine CXCL12.

Specifications

Catalog number
ET1611-3
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
ACKR3 antibody atypical chemokine receptor 3 antibody C X C chemokine receptor type 7 antibody C-X-C chemokine receptor type 7 antibody Chemokine (C-X-C motif) receptor 7 antibody Chemokine C X C motif receptor 7 antibody Chemokine orphan receptor 1 antibody CMKOR1 antibody CXC R7 antibody CXC-R7 antibody CXCR 7 antibody CXCR-7 antibody CXCR7 antibody CXCR7_HUMAN antibody G protein coupled receptor 159 antibody G protein coupled receptor antibody G protein coupled receptor RDC1 homolog antibody G-protein coupled receptor 159 antibody G-protein coupled receptor RDC1 homolog antibody GPR159 antibody GPRN1 antibody RDC 1 antibody RDC-1 antibody RDC1 antibody
Abbreviation
Atypical chemokine receptor, C-X-C chemokine receptor type 7 (CXC-R7; CXCR-7), Chemokine orphan receptor 1, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog (RDC-1), ACKR3, CMKOR1, CXCR7, GPR159, RDC1
Swiss Prot
P25106 Human, P56485 Mouse, O89039 Rat
Cellular Locus
Cell membrane, Early endosome, Recycling endosome.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human CXCR7 aa 313-362 / 362.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
HUVEC cell lysate, NIH/3T3 cell lysate, C6 cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 41 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for CXCR7 Recombinant Rabbit Monoclonal Antibody [SN65-09]?

The catalog number for CXCR7 Recombinant Rabbit Monoclonal Antibody [SN65-09] is ET1611-3.

What sizes are available for CXCR7 Recombinant Rabbit Monoclonal Antibody [SN65-09]?

CXCR7 Recombinant Rabbit Monoclonal Antibody [SN65-09] is available in the following size(s): 100 µL.

Is CXCR7 Recombinant Rabbit Monoclonal Antibody [SN65-09] in stock?

CXCR7 Recombinant Rabbit Monoclonal Antibody [SN65-09] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CXCR7 Recombinant Rabbit Monoclonal Antibody [SN65-09] used for?

Atypical chemokine receptor 3 also known as C-X-C chemokine receptor type 7 (CXCR-7) and G-protein coupled receptor 159 (GPR159) is a protein that in humans is encoded by the ACKR3 gene. This protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP) and was considered to b

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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