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Product details

MMP-11 Recombinant Rabbit Monoclonal Antibody [SN74-08]

Catalog number ET1611-33

Discontinued

Price for ET1611-33

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Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including Collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also called stromelysin-1, -2 and -3) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.

Specifications

Catalog number
ET1611-33
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
CAS Number
9000-83-3
Product Name Alternative
Matrix Metalloproteinase 11 antibody Matrix metalloproteinase-11 antibody MMP-11 antibody Mmp11 antibody MMP11_HUMAN antibody SL 3 antibody SL-3 antibody SL3 antibody ST3 antibody STMY3 antibody Stromelysin 3 antibody Stromelysin III antibody Stromelysin-3 antibody
Abbreviation
SL-3, ST3, MMP-11, MMP11
Swiss Prot
P24347 Human, Q02853 Mouse, Q499S5 Rat
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human MMP11 aa 439-488 / 488.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P
Positive Control
293T cell lysate, MCF7 cell lysate, mouse kidney tissue lysate, mouse lung tissue lysate, mouse testis tissue lysate, rat testis tissue lysate, SW480, MCF-7, A549, human spleen tissue, human breast carcinoma tissue, mouse spleen tissue.
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IF-Cell: 1:500-1:1,000 ;IF-Tissue: 1:500-1:1,000 ;IHC-P: 1:100-1:5000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 55 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for MMP-11 Recombinant Rabbit Monoclonal Antibody [SN74-08]?

The catalog number for MMP-11 Recombinant Rabbit Monoclonal Antibody [SN74-08] is ET1611-33.

Is MMP-11 Recombinant Rabbit Monoclonal Antibody [SN74-08] in stock?

MMP-11 Recombinant Rabbit Monoclonal Antibody [SN74-08] is currently made to order / not held in immediate stock. Contact us for lead time.

What is MMP-11 Recombinant Rabbit Monoclonal Antibody [SN74-08] used for?

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including Collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (L

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

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