AGR2 Recombinant Rabbit Monoclonal Antibody [SN74-01]

About this product

AGR2 (Anterior Gradient Protein 2), also known as AG2, GOB-4 or HAG-2, is a member of the anterior gradient homolog family. It is the human ortholog of XAG-2, the secreted Xenopus laevis Anterior Gradient protein. In X. laevis, it is involved in cement gland differentiation and neural marker gene expression. AGR2 is a secretory protein encoded by two different AGR2 transcripts. It interacts with LYPD3 and α-dystroglycan (DAG-1). AGR2 is ubiquitously expressed with up-regulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR). AGR2 may serve as a potential therapeutic marker for various cancers.

Specifications

Catalog number

ET1611-36

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

AG 2 antibody AG 2 protein antibody AG-2 antibody AG2 antibody AG2 protein antibody AGR 2 antibody AGR2 antibody AGR2_HUMAN antibody Anterior gradient 2 homolog (Xenopus laevis) antibody anterior gradient 2 homolog antibody Anterior gradient 2, Xenopus, homolog of antibody Anterior gradient homolog 2 antibody Anterior gradient protein 2 homolog antibody GOB 4 antibody GOB4 antibody HAG 2 antibody hAG-2 antibody hAG2 antibody HAG2/R antibody HPC 8 antibody hPC8 antibody PDIA17 antibody Protein disulfide isomerase family A member 17 antibody secreted cement gland homolog antibody Secreted cement gland protein XAG 2 homolog antibody Secreted cement gland protein XAG-2 homolog antibody Secreted cement gland protein XAG2 homolog antibody XAG 2 antibody XAG2 antibody

Abbreviation

AG-2, hAG-2, AGR2

Swiss Prot

O95994 Human, O88312 Mouse

Cellular Locus

Secreted, Endoplasmic reticulum.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Synthetic peptide within Human AGR2 aa 1-50 / 175.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, IP, FC

Positive Control

NIH/3T3 cell lysate, MCF-7 cell lysate, Hela cell lysate, Hela, MCF-7, NIH/3T3, human colon tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:5,000 ;IF-Cell: 1:100-1:500 ;IHC-P: 1:1,000 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 20 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes