MAP1LC3A Recombinant Rabbit Monoclonal Antibody [SN07-40]

About this product

Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and in maintaining the balance between neuronal plasticity and rigidity. MAP-light chain 3 beta (MAP-LC3β) and MAP-light chain 3 alpha (MAP-LC3α), both of which are mammalian homologs of yeast Apg8, are subunits that can associate with either MAP-1A or MAP-1B. While MAP-LC3β is essential for autophagy and is associated with autophagosome membranes after processing, MAP LC3α is involved in the formation of autophagosomal vacuoles and is localized to the intracytoplasmic membrane. MAP LC3α is expressed as two alternatively spliced isoforms that are expressed in testis, brain, heart, liver and skeletal muscle, but are absent in thymus and peripheral blood leukocytes.

Specifications

Catalog number

ET1611-37

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

ATG8E antibody Autophagy-related protein LC3 A antibody Autophagy-related ubiquitin-like modifier LC3 A antibody LC3 antibody LC3A antibody MAP1 light chain 3 like protein 1 antibody MAP1 light chain 3-like protein 1 antibody MAP1A/1B light chain 3 A antibody MAP1A/MAP1B LC3 A antibody MAP1A/MAP1B light chain 3 A antibody MAP1ALC3 antibody MAP1BLC3 antibody Map1lc3a antibody Microtubule associated proteins 1A/1B light chain 3 antibody Microtubule-associated protein 1 light chain 3 alpha antibody Microtubule-associated proteins 1A and 1B, light chain 3 antibody Microtubule-associated proteins 1A/1B light chain 3A antibody MLP3A_HUMAN antibody

Abbreviation

MAP1A/MAP1B LC3 A, MAP1LC3A

Swiss Prot

Q9H492 Human, Q91VR7 Mouse, Q6XVN8 Rat

Cellular Locus

Cytoplasm, Cytoplasmic vesicle, Cytoskeleton, Membrane, Microtubule.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of Human MAP1LC3A aa 1-103 / 121.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, IP

Positive Control

HeLa treated with 50μM Chloroquine for 18 hours cell lysate, C2C12 cell lysate, C2C12 treated with 50μM Chloroquine for 18 hours cell lysate, C6 cell lysate, C6 treated with 50μM Chloroquine for 18 hours cell lysate, mouse brain tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;IP: Use at an assay dependent concentration.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 14 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes