NSD3 Recombinant Rabbit Monoclonal Antibody [SN07-11]

About this product

The deduced 1,437 amino acid NSD3 protein contains two PWWP domains involved in protein-protein interactions, five PHD-type zinc finger motifs found in chromatin-associated proteins, a SAC (SET-associated cys-rich) domain, a SET domain and a C-terminal C5HCH domain. Two NSD3 variants have been identified. The short variant comprised of 645 amino acids, arises from alternative polyadenylation and exon splicing and contains a single PWWP domain. A longer NSD3 variant, which is only expressed in HeLa cells, is comprised of 1,388 amino acid residues. The human WHSC1L1 gene, which encodes the NSD3 protein, shares 68% and 55% identity with mouse Nsd1 and human WHSC1, respectively. Highest expression of NSD3 is observed in brain, heart and skeletal muscle tissues; lower levels of NSD3 expression are observed in the liver and lungs.

Specifications

Catalog number

ET1611-39

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

DKFZp667H044 antibody FLJ20353 antibody Histone lysine N methyltransferase NSD3 antibody Histone-lysine N-methyltransferase NSD3 antibody MGC126766 antibody MGC142029 antibody NSD 3 antibody NSD3_HUMAN antibody Nuclear set domain containing 3 antibody Nuclear SET domain containing protein 3 antibody Nuclear SET domain-containing protein 3 antibody pp14328 antibody Protein whistle antibody Whistle antibody WHSC1 like protein 1 antibody WHSC1-like 1 isoform 9 with methyltransferase activity to lysine antibody WHSC1-like protein 1 antibody WHSC1L1 antibody WHSC1L1 protein antibody Wolf Hirschhorn syndrome candidate 1 like 1 antibody Wolf-Hirschhorn syndrome candidate 1-like protein 1 antibody

Abbreviation

WHSC1-like protein 1, WHSC1L1

Swiss Prot

Q9BZ95 Human, Q6P2L6 Mouse, D3ZK47

Cellular Locus

Nucleus, Chromosome.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human NSD3 aa 1-50 / 1,437.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, FC, IHC-P

Positive Control

MCF-7 cell lysate, 293T cell lysate, human small intestine tissue, Hela, human lymph nodes tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000 ;FC: 1:50-1:100 ;IHC-P: 1:50-1:400

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 162 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes