TNFAIP3 Recombinant Rabbit Monoclonal Antibody [SN07-31] — image 1 of 3

Product details

TNFAIP3 Recombinant Rabbit Monoclonal Antibody [SN07-31]

Catalog number ET1611-40

Discontinued

Price for ET1611-40

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

A20 is a Cys2/Cys2 zinc finger protein that is induced by a variety of inflammatory stimuli and regulates gene expression. Specifically, A20 is induced by tumor necrosis factor (TNF) and interleukin 1 (IL-1), and acts as a negative regulator of nuclear factor κ B (NFκB) gene expression. By inhibiting NFκB activation, A20 plays a critical role in terminating NFκB responses to various stimuli. Although the C-terminal region of A20 contains seven zinc finger domains, only four of these domains are required for in vitro inhibition of TNF-induced NFκB activation. A20 also interacts with several other proteins, such as TRAF2, TRAF6 and IκB kinase (IKK) γ protein, and can thereby inhibit cell death. TXBP151, a novel A20-binding protein, may mediate the anti-apoptotic activity of A20. Involved in the negative feedback regulation of signal transduction, A20 and A20-binding proteins may be useful as novel therapeutic tools in the treatment of a variety of diseases.

Specifications

Catalog number: ET1611-40
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
CAS Number: 9000-83-3
Product Name Alternative: A20 antibody AISBL antibody MGC104522 antibody MGC138687 antibody MGC138688 antibody OTU domain containing protein 7C antibody OTU domain-containing protein 7C antibody OTUD7C antibody Putative DNA binding protein A20 antibody Putative DNA-binding protein A20 antibody TNAP3_HUMAN antibody TNF alpha-induced protein 3 antibody TNFA1P2 antibody TNFAIP 3 antibody TNFAIP3 (A20) antibody TNFAIP3 antibody Tumor necrosis factor alpha induced protein 3 antibody Tumor necrosis factor alpha-induced protein 3 antibody Tumor necrosis factor induced protein 3 antibody Tumor necrosis factor inducible protein A20 antibody tumor necrosis factor, alpha-induced protein 3 antibody Zinc finger protein A20 antibody
Abbreviation: TNF alpha-induced protein 3, TNFAIP3
Swiss Prot: P21580 Human
Cellular Locus: Cytoplasm, Nucleus, Lysosome.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within Human TNFAIP3 aa 491-540 / 790.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC
Positive Control: Jurkat cell lysates, Hela, A549, HepG2, human kidney tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000;IF-Cell: 1:100-1:500;IF-Tissue: 1:100-1:500;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 90 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for TNFAIP3 Recombinant Rabbit Monoclonal Antibody [SN07-31]?

The catalog number for TNFAIP3 Recombinant Rabbit Monoclonal Antibody [SN07-31] is ET1611-40.

Is TNFAIP3 Recombinant Rabbit Monoclonal Antibody [SN07-31] in stock?

TNFAIP3 Recombinant Rabbit Monoclonal Antibody [SN07-31] is currently made to order / not held in immediate stock. Contact us for lead time.

What is TNFAIP3 Recombinant Rabbit Monoclonal Antibody [SN07-31] used for?

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.