CD38 Recombinant Rabbit Monoclonal Antibody [SN07-20]

About this product

CD38 is a type II integral membrane glycoprotein which is present on early B and T cell lineages and activated B and T cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B cells, mitogen-activated T cells, monocytes and Ig-secreting plasma cells. CD38 acts as a NAD glycohydrolase in T lymphocytes. On hematopoietic cells CD38 induces activation, proliferation, and differentiation of mature T and B cells and mediates apoptosis of myeloid and lymphoid progenitor cells. In addition to acting as a signaling receptor, CD38 is also an enzyme capable of producing several calcium-mobilizing metabolites, including cyclic adenosine diphosphate ribose (cADPR). CD38 also plays a role in maintaining survival of an invariant NK T (iNKT) cell subset that preferentially contributes to the maintenance of immunological tolerance.

Specifications

Catalog number

ET1611-66

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Acute lymphoblastic leukemia cells antigen CD38 antibody ADP ribosyl cyclase 1 antibody ADP ribosyl cyclase antibody ADP ribosyl cyclase/cyclic ADP-ribose hydrolase antibody ADP-ribosyl cyclase 1 antibody ADPRC 1 antibody ADPRC1 antibody cADPr hydrolase 1 antibody CD 38 antibody CD38 antibody CD38 antigen (p45) antibody CD38 antigen antibody CD38 molecule antibody Cd38-rs1 antibody CD38_HUMAN antibody CD38H antibody Cyclic ADP ribose hydrolase antibody Cyclic ADP ribose hydrolase 1 antibody Cyclic ADP-ribose hydrolase 1 antibody EC 3.2.2.5 antibody Ecto nicotinamide adenine dinucleotide glycohydrolase antibody I-19 antibody I19 (mouse) antibody Lymphocyte differentiation antigen CD38 antibody NAD (+) nucleosidase antibody NIM-R5 antigen antibody NIMR5 antigen (mouse) antibody OTTHUMP00000158633 antibody OTTHUMP00000217743 antibody p45 antibody T10 antibody

Abbreviation

ADPRC 1, cADPr hydrolase 1, CD38

Swiss Prot

P28907 Human

Cellular Locus

Membrane.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within Human CD38 aa 251-300 / 300.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, FC, IF-Tissue

Positive Control

THP-1 cell lysates, Raji cell lysates, THP-1, human prostate tissue, human tonsil tissue, human peripheral blood lymphocytes, human appendix tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IHC-P: 1:8,000-1:50,000 ;FC: 1:1,000 ;IF-Tissue: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 34 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes