Cytokeratin 4 Recombinant Rabbit Monoclonal Antibody [SN74-03]

About this product

Cytokeratins are a subfamily of intermediate filament keratins that are characterized by a remarkable biochemical diversity, which is represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in isoelectric range between 4.9 and 7.8. Cytokeratin 1 has the highest molecular weight, while Cytokeratin 19 has the lowest molecular weight. The cytokeratins are divided into the type I and type II subgroups. Type II family members comprise the basic to neutral members, Cytokeratins 1-8, while the type I group comprises the acidic members, Cytokeratins 9-20. Various epithelia in the human body usually express cytokeratins which are characteristic of the type of epithelium and related to the degree of maturation or differentiation within said epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. Cytokeratin 4 is expressed in differentiated layers of the mucosal and esophageal epithelia along with Cytokeratin 13.

Specifications

Catalog number

ET1611-71

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

CK 4 antibody CK-4 antibody CK4 antibody CYK4 antibody Cytokeratin 4 antibody Cytokeratin-4 antibody Cytokeratin4 antibody FLJ31692 antibody K2C4_HUMAN antibody K4 antibody Keratin 4 antibody Keratin antibody Keratin type II cytoskeletal 4 antibody Keratin-4 antibody Keratin4 antibody KRT 4 antibody Krt4 antibody type II cytoskeletal 4 antibody Type-II keratin Kb4 antibody

Abbreviation

CK-4, K4, KRT4

Swiss Prot

P19013 Human

Cellular Locus

Cell surface, intermediate filament cytoskeleton, nucleus.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within Human Cytokeratin 4 aa 395-520 / 520.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC, IP

Positive Control

A431, human tonsil tissue, human esophagus tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:100-1:500 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 56 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes