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Product details

MUC16 Recombinant Rabbit Monoclonal Antibody [SN0715]

Catalog number ET1611-73

Price for ET1611-73

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Size / count 100 µL

About this product

The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

Specifications

Catalog number
ET1611-73
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
CA 125 antibody CA-125 antibody CA125 antibody CA125 ovarian cancer antigen antibody Cancer antigen 125 antibody FLJ14303 antibody MUC 16 antibody MUC-16 antibody MUC16 antibody MUC16_HUMAN antibody Mucin 16 antibody Mucin 16 cell surface associated antibody Mucin-16 antibody Mucin16 antibody Ovarian cancer related tumor marker CA125 antibody Ovarian cancer-related tumor marker CA125 antibody Ovarian carcinoma antigen CA125 antibody
Abbreviation
MUC-16, CA-125, MUC16
Swiss Prot
Q8WXI7 Human
Cellular Locus
Cell membrane, extracellular space.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human MUC16 aa 12331-12339 / 14,507.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, FC
Positive Control
SK-OV-3 cell lysate, NIH:OVCAR-3 cell lysate, HepG2, Hela, SKOV-3, human endometrium tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IF-Cell: 1:100-1:500 ;IF-Tissue: 1:200 ;IHC-P: 1:1,000 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 1519 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for MUC16 Recombinant Rabbit Monoclonal Antibody [SN0715]?

The catalog number for MUC16 Recombinant Rabbit Monoclonal Antibody [SN0715] is ET1611-73.

What sizes are available for MUC16 Recombinant Rabbit Monoclonal Antibody [SN0715]?

MUC16 Recombinant Rabbit Monoclonal Antibody [SN0715] is available in the following size(s): 100 µL.

Is MUC16 Recombinant Rabbit Monoclonal Antibody [SN0715] in stock?

MUC16 Recombinant Rabbit Monoclonal Antibody [SN0715] is currently made to order / not held in immediate stock. Contact us for lead time.

What is MUC16 Recombinant Rabbit Monoclonal Antibody [SN0715] used for?

The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithe

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

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