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Product details

FosB Recombinant Rabbit Monoclonal Antibody [SN703]

Catalog number ET1611-75

Price for ET1611-75

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Size / count 100 µL

About this product

The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes.

Specifications

Catalog number
ET1611-75
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Activator protein 1 antibody AP 1 antibody DKFZp686C0818 antibody FBJ murine osteosarcoma viral oncogene homolog B antibody fosB antibody FOSB_HUMAN antibody G0/G1 switch regulatory protein 3 antibody G0S3 antibody GOS 3 antibody GOS B antibody GOS3 antibody GOSB antibody MGC42291 antibody Oncogene FOS B antibody Oncogene FOSB antibody Protein fos B antibody Protein fosB antibody
Abbreviation
FOSB
Swiss Prot
P53539 Human, P13346 Mouse,
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human FosB aa 6-189 / 338.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IP
Positive Control
SK-Br-3 cell lysates, human tonsil tissue, mouse hippocampus tissue, mouse brain tissue, mouse spleen tissue, rat spleen tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:50-1:2,000 ;IP: Use at an assay dependent concentration.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 36 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for FosB Recombinant Rabbit Monoclonal Antibody [SN703]?

The catalog number for FosB Recombinant Rabbit Monoclonal Antibody [SN703] is ET1611-75.

What sizes are available for FosB Recombinant Rabbit Monoclonal Antibody [SN703]?

FosB Recombinant Rabbit Monoclonal Antibody [SN703] is available in the following size(s): 100 µL.

Is FosB Recombinant Rabbit Monoclonal Antibody [SN703] in stock?

FosB Recombinant Rabbit Monoclonal Antibody [SN703] is currently made to order / not held in immediate stock. Contact us for lead time.

What is FosB Recombinant Rabbit Monoclonal Antibody [SN703] used for?

The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

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