Calnexin Recombinant Rabbit Monoclonal Antibody [SN20-54]

About this product

Calnexin and Calregulin (also called calreticulin) are calcium-binding proteins that are localized to the endoplasmic reticulum, Calnexin to the membrane and Calregulin to the lumen. Calnexin is a type I membrane protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may play a role in assisting with protein assembly and in retaining unassembled protein subunits in the endoplasmic reticulum. Calregulin has both low- and high-affinity calcium-binding sites. Neither Calnexin nor Calregulin contains the calcium-binding “E-F hand” motif found in calmodulins. Calnexin and Calregulin are important for the maturation of glycoproteins in the endoplasmic reticulum and appear to bind many of the same proteins.

Specifications

Catalog number

ET1611-86

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Calnexin antibody CALX_HUMAN antibody CANX antibody CNX antibody FLJ26570 antibody Histocompatibility complex class I antigen binding protein p88 antibody IP90 antibody Major histocompatibility complex class I antigen-binding protein p88 antibody p90 antibody

Abbreviation

CANX

Swiss Prot

P27824 Human

Cellular Locus

Endoplasmic reticulum membrane, Endoplasmic reticulum, Melanosome.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within Human Calnexin aa 543-592 / 592.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, FC, IP

Positive Control

HeLa cell lysate, HepG2 cell lysate, MCF7 cell lysate, PANC-1 cell lysate, Hela, HepG2, PANC-1.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000 ;IF-Cell: 1:100-1:500 ;FC: 1:50-1:100 ;IP: 1-2μg/sample

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 68 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes