RAB7 Recombinant Rabbit Monoclonal Antibody [SN202-03]

About this product

The Ras-related superfamily of guanine nucleotide binding proteins, which includes the Ral/Rec, Rap, R-Ras, and Rho/Rab subfamilies, exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the Sec4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles. Several members of the Rab subfamily have been identified, each of which is found at a particular stage of a membrane transport pathway.

Specifications

Catalog number

ET1611-96

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

CAS Number

9000-83-3

Product Name Alternative

CMT2B antibody PRO2706 antibody PSN antibody RAB7, member RAS oncogene family antibody RAB7A antibody RAB7A, member RAS oncogene family antibody RAB7A_HUMAN antibody Ras associated protein RAB7 antibody Ras related protein Rab7 antibody Ras related protein Rab7a antibody Ras-related protein Rab-7a antibody

Abbreviation

RAB7A

Swiss Prot

P51149 Human, P51150 Mouse, P09527 Rat

Cellular Locus

Cytoplasmic vesicle, Lysosome membrane, Melanosome membrane, Lipid droplet.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human RAB7 aa 158-207 / 207.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC

Positive Control

HeLa cell lysate, MCF7 cell lysate, Neuro-2a cell lysate, C2C12 cell lysate, PC-12 cell lysate, C6 cell lysate, Hela, SW480, NIH/3T3, human colon carcinoma tissue, human kidney tissue, mouse skeletal tissue, mouse kidney tissue, K562.

Concentration

1 mg/mL

Dilution

WB: 1:5,000 ;IF-Cell: 1:100-1:1,000 ;IF-Tissue: 1:100-1:500 ;IHC-P: 1:50-1:1,000 ;FC: 1:500-1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 23 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes