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Product details

Cdk8 Recombinant Rabbit Monoclonal Antibody [SN2030]

Catalog number ET1611-99

Price for ET1611-99

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Size / count 100 µL

About this product

Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Several Cdk proteins have been identified, including Cdk2-Cdk8, PCTAIRE-1–3, PITALRE and PITSLRE. Large complexes containing Cdk8, cyclin C and the large subunit of RNA polymerase II have been identified. Cdk8 is thought to regulate RNA polymerase II function in conjunction with cyclin C. Cdk8 has been demonstrated to function as a transcriptional activator when fused to the DNA binding domain of GAL4.

Specifications

Catalog number
ET1611-99
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
cdk8 antibody CDK8 protein kinase antibody CDK8_HUMAN antibody Cell Division Kinase 8 antibody Cell division protein kinase 8 antibody Cyclin Dependent kinase 8 antibody Cyclin-dependent kinase 8 antibody K35 antibody Mediator complex subunit cdk8 antibody Mediator of RNA polymerase II transcription subunit cdk8 antibody Protein kinase K35 antibody
Abbreviation
CDK8
Swiss Prot
P49336 Human, Q8R3L8 Mouse
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human CDK8 aa 1-50 / 464.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
A549 cell lysate, Human liver tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 53 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Cdk8 Recombinant Rabbit Monoclonal Antibody [SN2030]?

The catalog number for Cdk8 Recombinant Rabbit Monoclonal Antibody [SN2030] is ET1611-99.

What sizes are available for Cdk8 Recombinant Rabbit Monoclonal Antibody [SN2030]?

Cdk8 Recombinant Rabbit Monoclonal Antibody [SN2030] is available in the following size(s): 100 µL.

Is Cdk8 Recombinant Rabbit Monoclonal Antibody [SN2030] in stock?

Cdk8 Recombinant Rabbit Monoclonal Antibody [SN2030] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cdk8 Recombinant Rabbit Monoclonal Antibody [SN2030] used for?

Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a ro

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

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