- Home
- Shop
- New Categories
- New Blog
- Contact Us
- Cart
- Login
- Register
![Cyclin B2 Recombinant Rabbit Monoclonal Antibody [SD2045] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea81926/imageurl/et1612-21.webp)
Product details
Catalog number ET1612-21
Price for ET1612-21
Size / count 100 µL
In eukaryotic cells, mitosis is initiated following the activation of a protein kinase known variously as maturation-promoting factor, M-phase specific histone kinase or M-phase kinase. This protein kinase is composed of a catalytic subunit (Cdc2), a regulatory subunit (cyclin B) and a low molecular weight subunit (p13-Suc 1). The Cdc/cyclin enzyme is subject to multiple levels of control of which the regulation of the catalytic subunit by tyrosine phosphorylation is the best understood. Tyrosine phosphorylation inhibits the Cdc2/cyclin B enzyme and tyrosine dephosphorylation, occurring at the onset of mitosis, directly activates the pre-MPF complex . Evidence has established that B-type cyclins not only act on M-phase regulatory subunits of the Cdc2 protein kinase, but also activate the Cdc25A and Cdc25B endogenous tyrosine phosphatase, of which Cdc2 is the physiological substrate. The two B-type cyclins, cyclin B1 and cyclin B2, have been shown to have distinct tissue distributions.
The catalog number for Cyclin B2 Recombinant Rabbit Monoclonal Antibody [SD2045] is ET1612-21.
Cyclin B2 Recombinant Rabbit Monoclonal Antibody [SD2045] is available in the following size(s): 100 µL.
Cyclin B2 Recombinant Rabbit Monoclonal Antibody [SD2045] is currently made to order / not held in immediate stock. Contact us for lead time.
In eukaryotic cells, mitosis is initiated following the activation of a protein kinase known variously as maturation-promoting factor, M-phase specific histone kinase or M-phase kinase. This protein kinase is composed of a catalytic subunit (Cdc2), a regulatory subunit (cyclin B) and a low molecular
Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.
Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.
A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.
