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Product details

Histone H1.0 Recombinant Rabbit Monoclonal Antibody [SD206-04]

Catalog number ET1612-24

Price for ET1612-24

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Size / count 100 µL

About this product

Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene, that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.

Specifications

Catalog number
ET1612-24
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
H1 histone family member 0 antibody H1 (0) antibody H10 antibody H10_HUMAN antibody h1f0 antibody H1FV antibody Histone H1' antibody Histone H1 (0) antibody Histone H1.0 antibody Histone H10 antibody Histone H5 antibody MGC5241 antibody N-terminally processed antibody
Abbreviation
H1F0
Swiss Prot
P07305 Human, P10922 Mouse, P43278 Rat
Cellular Locus
Nucleus, Chromosome.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human Histone H10 aa 1-50 / 194.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P
Positive Control
NIH/3T3 cell lysate, PC-3 cell lysate, NIH/3T3, human tonsil tissue, human colon carcinoma tissue, human pancreas tissue, mouse colon tissue, human kidney tissue, mouse liver tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000;IF-Cell: 1:50-1:100;IF-Tissue: 1:50-1:100;IHC-P: 1:50-1:800
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 21 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Histone H1.0 Recombinant Rabbit Monoclonal Antibody [SD206-04]?

The catalog number for Histone H1.0 Recombinant Rabbit Monoclonal Antibody [SD206-04] is ET1612-24.

What sizes are available for Histone H1.0 Recombinant Rabbit Monoclonal Antibody [SD206-04]?

Histone H1.0 Recombinant Rabbit Monoclonal Antibody [SD206-04] is available in the following size(s): 100 µL.

Is Histone H1.0 Recombinant Rabbit Monoclonal Antibody [SD206-04] in stock?

Histone H1.0 Recombinant Rabbit Monoclonal Antibody [SD206-04] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Histone H1.0 Recombinant Rabbit Monoclonal Antibody [SD206-04] used for?

Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form t

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

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