AP2M1 Recombinant Rabbit Monoclonal Antibody [SD0746]

About this product

Adaptins are heterotetrameric subunits of adaptors, which are complexes involved in the formation of Clathrin-coated pits for vesicle-mediated endocytosis. Clathrin and its associated heterotetrameric protein complexes make up the main protein components of the coat surrounding the cytoplasmic face of coated vesicles. The Adaptin family, comprising a, b, b' and g classes, is also responsible for the transport of ligand-receptor complexes from plasma membranes and the trans-Golgi network to lysosomes. Two main types of adaptor proteins (APs), AP-1 and AP-2, are found in Clathrin-coated structures located at the Golgi complex and the plasma membrane of mammalian cells, respectively. Adaptor protein complex 2 (AP-2) is composed of two large Adaptins (a1A/AP2A1 and b1/AP2B1), a medium Adaptin (m2/AP-2m1) and a small Adaptin (s2 long/AP2S1). AP-2m1, a 435 amino acid protein, links Clathrin to receptors in coated vesicles.

Specifications

Catalog number

ET1612-33

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Adapter-related protein complex 2 mu subunit antibody Adaptin mu 1 antibody Adaptin-mu2 antibody Adaptor protein complex AP 2 subunit mu antibody Adaptor protein complex AP-2 subunit mu antibody Adaptor related protein complex 2 mu 1 subunit antibody AP 2 mu 2 chain antibody AP-2 complex subunit mu antibody AP-2 mu chain antibody Ap2m1 antibody AP2M1_HUMAN antibody AP50 antibody CLAPM1 antibody Clathrin adaptor complex AP2 mu subunit antibody Clathrin assembly protein complex 2 medium chain antibody Clathrin associated/assembly/adaptor protein medium 1 antibody Clathrin coat adaptor protein AP50 antibody Clathrin coat assembly protein AP50 antibody Clathrin coat associated protein AP50 antibody Clathrin coat-associated protein AP50 antibody HA2 50 kDa subunit antibody mu2 antibody Plasma membrane adaptor AP-2 50 kDa protein antibody

Abbreviation

AP2M1

Swiss Prot

Q96CW1 Human, P84091 Mouse, P84092 Rat

Cellular Locus

Cell membrane, coated pit.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human AP2M1 aa 351-400 / 435.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

PC-3M cell lysates, HepG2, SH-SY5Y, MCF-7, human kidney tissue, mouse brain tissue, PANC-1.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

50 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes