MEK7 Recombinant Rabbit Monoclonal Antibody [SD20-87]

About this product

A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.

Specifications

Catalog number

ET1612-35

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

c-Jun N-terminal kinase kinase 2 antibody Dual specificity mitogen activated protein kinase kinase 7 antibody Dual specificity mitogen-activated protein kinase kinase 7 antibody JNK activating kinase 2 antibody JNK kinase 2 antibody JNK-activating kinase 2 antibody JNKK 2 antibody Jnkk-2 antibody Jnkk2 antibody MAP kinase kinase 7 antibody MAP2K7 antibody MAPK/ERK kinase 7 antibody MAPKK 7 antibody MAPKK-7 antibody MAPKK7 antibody MEK 7 antibody Mitogen Activated Protein Kinase kinase 7 antibody MKK 7 antibody MKK-7 antibody MKK7 antibody MP2K7_HUMAN antibody PRKMK 7 antibody PRKMK-7 antibody PRKMK7 antibody SAPK kinase 4 antibody SAPKK-4 antibody SAPKK4 antibody Sek 2 antibody Sek-2 antibody Sek2 antibody SKK4 antibody stress-activated protein kinase kinase 4 antibody

Abbreviation

MAP kinase kinase 7, MAPKK 7, MEK 7, SAPK kinase 4, SAPKK-4, SAPKK4, JNK kinase 2, JNKK 2, MAP2K7

Swiss Prot

O14733 Human, Q8CE90 Mousen, Q4KSH7 Rat

Cellular Locus

Nucleus, Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human MEK7 aa 370-419 / 419.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, IP, FC

Positive Control

A431, SHG-44, Hela, SH-SY-5Y, rat brain tissue, rat bladder tissue, mouse bladder tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 47 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes