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Product details

IRF6 Recombinant Rabbit Monoclonal Antibody [SD202-6]

Catalog number ET1612-36

Price for ET1612-36

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Size / count 100 µL

About this product

Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-α and β) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-α and interferon-β genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth; overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3γ p48 and IFN consensus sequence-binding protein (ICSBP).

Specifications

Catalog number
ET1612-36
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Interferon regulatory factor 6 antibody IRF 6 antibody IRF-6 antibody IRF6 antibody IRF6_HUMAN antibody LPS antibody OFC 6 antibody OFC6 antibody OTTHUMP00000034677 antibody OTTHUMP00000034678 antibody PIT antibody PPS antibody PPS1 antibody VWS antibody VWS1 antibody
Abbreviation
IRF-6, IRF6
Swiss Prot
O14896 Human, P97431 Mouse,
Cellular Locus
Nucleus, Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein Human IRF6 aa 364-467 / 467.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P
Positive Control
K562, MCF-7, 293, SW480, human kidney tissue, mouse kidney tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
60 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for IRF6 Recombinant Rabbit Monoclonal Antibody [SD202-6]?

The catalog number for IRF6 Recombinant Rabbit Monoclonal Antibody [SD202-6] is ET1612-36.

What sizes are available for IRF6 Recombinant Rabbit Monoclonal Antibody [SD202-6]?

IRF6 Recombinant Rabbit Monoclonal Antibody [SD202-6] is available in the following size(s): 100 µL.

Is IRF6 Recombinant Rabbit Monoclonal Antibody [SD202-6] in stock?

IRF6 Recombinant Rabbit Monoclonal Antibody [SD202-6] is currently made to order / not held in immediate stock. Contact us for lead time.

What is IRF6 Recombinant Rabbit Monoclonal Antibody [SD202-6] used for?

Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-α and β) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which conf

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

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