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Product details

ATF4 Recombinant Rabbit Monoclonal Antibody [SD20-92]

Catalog number ET1612-37

Discontinued

Price for ET1612-37

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Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

Eukaryotic gene transcription is regulated by sequence-specific transcription factors which bind modular cis-acting promoter and enhancer elements. The cAMP response element (CRE), one of the best studied of such elements, consists of the palindromic octanucleotide TGACGTCA. Several CRE binding proteins have been identified within the ATF/CREB family, the best characterized of which include CREB-1, CREB-2 (also designated ATF-4), ATF-1, ATF-2 and ATF-3. These proteins share highly related COOH terminal leucine zipper dimerization and basic DNA binding domains but are highly divergent in their amino terminal domains. Although each of the ATF/CREB proteins appear capable of binding CRE in its homodimeric form, certain of these also bind as heterodimers, both within the ATF/CREB family and even with members of the AP-1 transcription factor family.

Specifications

Catalog number
ET1612-37
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
CAS Number
9000-83-3
Product Name Alternative
Activating transcription factor 4 antibody ATF 4 antibody ATF4 antibody ATF4 protein antibody ATF4_HUMAN antibody cAMP-dependent transcription factor ATF-4 antibody cAMP-responsive element-binding protein 2 antibody CREB 2 antibody CREB-2 antibody CREB2 antibody Cyclic AMP dependent transcription factor ATF 4 antibody Cyclic AMP response element binding protein 2 antibody Cyclic AMP-dependent transcription factor ATF-4 antibody Cyclic AMP-responsive element-binding protein 2 antibody DNA binding protein TAXREB67 antibody DNA-binding protein TAXREB67 antibody Tax Responsive Enhancer Element B67 antibody Tax-responsive enhancer element-binding protein 67 antibody TaxREB67 antibody TXREB antibody
Abbreviation
cAMP-dependent transcription factor ATF-4, CREB-2, cAMP-responsive element-binding protein 2, TaxREB67, ATF4
Swiss Prot
P18848 Human, Q06507 Mouse, Q9ES19 Rat
Cellular Locus
Nucleus, Nucleus speckle, Cell membrane, Cytoplasm, Centrosome.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human ATF4 aa 1-220 / 351.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
Positive Control
Hela cell lysate, PC-12 cell lysate, HL-60 cell lysate, K562 cell lysate, human lung carcinoma tissue lysate, N2A, human liver carcinoma tissue, human prostate carcinoma tissue, human skin tissue, human breast carcinoma tissue, human stomach carcinoma tissue, human small intestine tissue, human colon carcinoma tissue, Hela, mouse testis tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:1,000 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 39 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for ATF4 Recombinant Rabbit Monoclonal Antibody [SD20-92]?

The catalog number for ATF4 Recombinant Rabbit Monoclonal Antibody [SD20-92] is ET1612-37.

Is ATF4 Recombinant Rabbit Monoclonal Antibody [SD20-92] in stock?

ATF4 Recombinant Rabbit Monoclonal Antibody [SD20-92] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ATF4 Recombinant Rabbit Monoclonal Antibody [SD20-92] used for?

Eukaryotic gene transcription is regulated by sequence-specific transcription factors which bind modular cis-acting promoter and enhancer elements. The cAMP response element (CRE), one of the best studied of such elements, consists of the palindromic octanucleotide TGACGTCA. Several CRE binding prot

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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