ATF5 Recombinant Rabbit Monoclonal Antibody [SD2099]

About this product

Eukaryotic gene transcription is regulated by sequence-specific transcription factors that bind modular cis acting promoter and enhancer elements. The ATF/CREB transcription factor family binds the palindromic cAMP response element (CRE) octanucleotide TGACGTCA. The best characterized members of this gene family include CREB-1, CREB-2 (also designated ATF-4), CRE-BPa, LZIP (also designated CREB3 and Luman), CREM-1, CREM-2, ATF-1, ATF-2, ATF-3, ATF-5, ATF-6 and ATF-7. This family of proteins contain highly divergent N-terminal domains, but share a C-terminal leucine zipper for dimerization and DNA binding. ATF-5 (ATFx), which can localize to the cytoplasm or the nucleus, binds DNA as a dimer. It interacts with CCND3 and PTP4A1.

Specifications

Catalog number

ET1612-38

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

CAS Number

9000-83-3

Product Name Alternative

Activating transcription factor 5 alpha/beta antibody Activating transcription factor 5 antibody Activating transcription factor X antibody AFTA antibody ATF 5 antibody ATF 7 antibody ATF7 antibody ATFX antibody BZIP protein ATF7 antibody cAMP dependent transcription factor ATF 5 antibody cAMP dependent transcription factor ATF5 antibody Cyclic AMP dependent transcription factor ATF 5 antibody Cyclic AMP dependent transcription factor ATF5 antibody FLJ34666 antibody HMFN0395 antibody MGC102397 antibody NAP1 antibody NRIF3 associated protein antibody ODA 10 antibody Transcription factor ATFx antibody Transcription factor like protein ODA 10 antibody Transcription factor like protein ODA10 antibody

Abbreviation

cAMP-dependent transcription factor ATF-5, ATF5

Swiss Prot

Q9Y2D1 Human, O70191 Mouse, Q6P788 Rat

Cellular Locus

Centrosome, Nucleus, Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human ATF5 aa 203-252 / 282.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, IP, FC

Positive Control

HEK-293 cell lysate, Jurkat cell lysate, NIH/3T3 cell lysate, RAW264.7 cell lysate, C6 cell lysate, PC-12 cell lysate, HeLa, RAW264.7, C6, human liver tissue, human stomach tissue, mouse liver tissue, mouse stomach tissue, rat liver tissue, rat stomach tissue.

Concentration

1 mg/mL

Dilution

WB: 1:2,000 ;IF-Cell: 1:100 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:200-1:1,000 ;IP: 1-2μg/sample ;FC: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 31 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes