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![Cyclin D3 Recombinant Rabbit Monoclonal Antibody [SD20-43] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8e061270361ea82640/imageurl/et1612-4.webp)
Product details
Catalog number ET1612-4
Price for ET1612-4
Size / count 100 µL
The proliferation of eukaryotic cells is controlled at specific points in the cell cycle, particularly at the G1 to S and the G2 to M transitions. It is well established that the Cdc2 p34-cyclin B protein kinase plays a critical role in the G2 to M transition while cyclin A associates with Cdk2 p33 and functions in S phase. Considerable effort directed towards the identification of G1 cyclins has led to the isolation of cyclin D, cyclin C and cyclin. Of these, cyclin D corresponds to a putative human oncogene, designated PRAD1, which maps at the site of the Bcl-1 rearrangement in certain lymphomas and leukemias. Two additional human type D cyclins, as well as their mouse homologs, have been identified. Evidence has established that members of the cyclin D family function to regulate phosphorylation of the retinoblastoma gene product, thereby activating E2F transcription factors.
The catalog number for Cyclin D3 Recombinant Rabbit Monoclonal Antibody [SD20-43] is ET1612-4.
Cyclin D3 Recombinant Rabbit Monoclonal Antibody [SD20-43] is available in the following size(s): 100 µL.
Cyclin D3 Recombinant Rabbit Monoclonal Antibody [SD20-43] is currently made to order / not held in immediate stock. Contact us for lead time.
The proliferation of eukaryotic cells is controlled at specific points in the cell cycle, particularly at the G1 to S and the G2 to M transitions. It is well established that the Cdc2 p34-cyclin B protein kinase plays a critical role in the G2 to M transition while cyclin A associates with Cdk2 p33
A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.
Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.
Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.
