Phospho-MEK1 (T292) Recombinant Rabbit Monoclonal Antibody [SD2088]

Catalog number ET1612-42

Price for ET1612-42

Size / count 100 µL

About this product

A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK 5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.

Specifications

Catalog number: ET1612-42
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Dual specificity mitogen activated protein kinase kinase 1 antibody Dual specificity mitogen-activated protein kinase kinase 1 antibody ERK activator kinase 1 antibody MAP kinase kinase 1 antibody MAP kinase/Erk kinase 1 antibody MAP2K1 antibody MAPK/ERK kinase 1 antibody MAPKK 1 antibody MAPKK1 antibody MEK 1 antibody Mek1 antibody MEKK1 antibody Mitogen activated protein kinase kinase 1 antibody MKK 1 antibody MKK1 antibody MP2K1_HUMAN antibody PRKMK1 antibody Protein kinase mitogen activated kinase 1 (MAP kinase kinase 1) antibody Protein kinase mitogen activated, kinase 1 antibody
Abbreviation: MAP kinase kinase 1, MAPKK 1, MKK1, MEK 1, MAP2K1
Swiss Prot: Q02750 Human, P31938 Mouse, Q01986 Rat
Cellular Locus: Cytoplasm, Nucleus, Membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Thr292 of Human MEK1 aa 271-320 / 393.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: HeLa cell lysate, HeLa treated with 100ng/mL Nocodazole for 17 hours cell lysate, PC-12 cell lysate, PC-12 treated with 100ng/mL Nocodazole for 18 hours cell lysate, NIH/3T3 cell lysate, NIH/3T3 treated with 100ng/mL Nocodazole for 18 hours cell lysate, mouse brain tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000 ;IHC-P: 1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 43 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Phospho-MEK1 (T292) Recombinant Rabbit Monoclonal Antibody [SD2088]?

The catalog number for Phospho-MEK1 (T292) Recombinant Rabbit Monoclonal Antibody [SD2088] is ET1612-42.

What sizes are available for Phospho-MEK1 (T292) Recombinant Rabbit Monoclonal Antibody [SD2088]?

Phospho-MEK1 (T292) Recombinant Rabbit Monoclonal Antibody [SD2088] is available in the following size(s): 100 µL.

Is Phospho-MEK1 (T292) Recombinant Rabbit Monoclonal Antibody [SD2088] in stock?

Phospho-MEK1 (T292) Recombinant Rabbit Monoclonal Antibody [SD2088] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Phospho-MEK1 (T292) Recombinant Rabbit Monoclonal Antibody [SD2088] used for?

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.