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Product details

HDAC4 Recombinant Rabbit Monoclonal Antibody [SD08-35]

Catalog number ET1612-51

Price for ET1612-51

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Size / count 100 µL

About this product

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, p300/CBP, PCAF (p300/CBPassociated factor), HAT1, and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3-6, have been identified as histone deacetylases.

Specifications

Catalog number
ET1612-51
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
AHO3 antibody BDMR antibody EC 3.5.1.98 antibody HA6116 antibody HD 4 antibody HD4 antibody HDAC 4 antibody HDAC A antibody HDAC4 antibody HDAC4_HUMAN antibody HDACA antibody Histone deacetylase 4 antibody Histone Deacetylase A antibody KIAA0288 antibody
Abbreviation
HD4, HDAC4
Swiss Prot
P56524 Human
Cellular Locus
Nucleus, Cytoplasm.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human HDAC4 aa 11-125/1084.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, FC
Positive Control
HCT 116 cell lysate, human colon cancer tissue, human testis tissue, Hela, A549, HepG2.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IF-Cell: 1:100-1:500 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:200 ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 119 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for HDAC4 Recombinant Rabbit Monoclonal Antibody [SD08-35]?

The catalog number for HDAC4 Recombinant Rabbit Monoclonal Antibody [SD08-35] is ET1612-51.

What sizes are available for HDAC4 Recombinant Rabbit Monoclonal Antibody [SD08-35]?

HDAC4 Recombinant Rabbit Monoclonal Antibody [SD08-35] is available in the following size(s): 100 µL.

Is HDAC4 Recombinant Rabbit Monoclonal Antibody [SD08-35] in stock?

HDAC4 Recombinant Rabbit Monoclonal Antibody [SD08-35] is currently made to order / not held in immediate stock. Contact us for lead time.

What is HDAC4 Recombinant Rabbit Monoclonal Antibody [SD08-35] used for?

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. A

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

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