Stromal interaction molecule 1 Recombinant Rabbit Monoclonal Antibody [SD0814] — image 1 of 3

Product details

Stromal interaction molecule 1 Recombinant Rabbit Monoclonal Antibody [SD0814]

Catalog number ET1612-53

Price for ET1612-53

Size / count 100 µL

About this product

Ca2+ influx is essential for a variety of cellular functions including, secretion and transcription. Stromal interaction molecule 1 (Stim1) is a ubiquitously expressed cell surface transmembrane glycoprotein that plays a role in medi-ating Ca2+ influx following the depletion of intracellular Ca2+ stores. Stim1 functions in the endoplasmic reticulum (ER) where it acts as a Ca2+ sensor via its EF-hand domain which causes large conformational changes. When Ca2+ levels drop, Stim1 translocates from the ER to the plasma membrane, where it activates the Ca2+ release-activated Ca2+ (CRAC) channel subunit, TMEM142A/Orai1. Stim2 is a potent inhibitor of Stim1-mediated store-operated calcium (SOC) entry. Stim1 is implicated in tumor growth suppression and stromal-hematopoietic cell interactions.

Specifications

Catalog number: ET1612-53
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: D11S4896E antibody GOK antibody OTTHUMP00000164512 antibody OTTHUMP00000229140 antibody OTTHUMP00000230742 antibody SIM antibody STIM 1 antibody STIM1 antibody Stim1 stromal interaction molecule 1 antibody STIM1_HUMAN antibody STIM1L antibody Stromal interaction molecule 1 antibody
Abbreviation: STIM1
Swiss Prot: Q13586 Human, P70302 Mouse, P84903 Rat
Cellular Locus: Cell membrane, Endoplasmic reticulum membrane, Cytoplasm, Sarcoplasmic reticulum.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human Stromal aa 561-685 / 685.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, IP
Positive Control: K-562, HepG2, Human thyroid tissue, mouse skeletal muscle tissue, mouse testis tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 100 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Stromal interaction molecule 1 Recombinant Rabbit Monoclonal Antibody [SD0814]?

The catalog number for Stromal interaction molecule 1 Recombinant Rabbit Monoclonal Antibody [SD0814] is ET1612-53.

What sizes are available for Stromal interaction molecule 1 Recombinant Rabbit Monoclonal Antibody [SD0814]?

Stromal interaction molecule 1 Recombinant Rabbit Monoclonal Antibody [SD0814] is available in the following size(s): 100 µL.

Is Stromal interaction molecule 1 Recombinant Rabbit Monoclonal Antibody [SD0814] in stock?

Stromal interaction molecule 1 Recombinant Rabbit Monoclonal Antibody [SD0814] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Stromal interaction molecule 1 Recombinant Rabbit Monoclonal Antibody [SD0814] used for?

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.