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![PAX6 Recombinant Rabbit Monoclonal Antibody [SD081-03] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8d061270361ea81e60/imageurl/et1612-58.webp)
Product details
Catalog number ET1612-58
Price for ET1612-58
Size / count 100 µL
Pax genes contain paired domains with strong homology to genes in Drosophila which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
The catalog number for PAX6 Recombinant Rabbit Monoclonal Antibody [SD081-03] is ET1612-58.
PAX6 Recombinant Rabbit Monoclonal Antibody [SD081-03] is available in the following size(s): 100 µL.
PAX6 Recombinant Rabbit Monoclonal Antibody [SD081-03] is currently made to order / not held in immediate stock. Contact us for lead time.
Pax genes contain paired domains with strong homology to genes in Drosophila which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. P
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