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Product details

Tyrosine Hydroxylase Recombinant Rabbit Monoclonal Antibody [SD080-02]

Catalog number ET1612-65

Price for ET1612-65

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Size / count 100 µL

About this product

The enzyme tyrosine hydroxylase (TH), also designated tyrosine 3-monooxygenase (TY3H), catalyzes the conversion of tyrosine to L-dopa, which is the rate limiting step in the biosynthesis of catecholamines such as dopamine, adrenalin and noradrenalin. TH is thought to play a role in the pathogenesis of Parkinson’s disease, which is associated with reduced dopamine levels. Two transcription factor binding sites in the proximal region of the TH gene, the TPA-responsive element (TRE) and the c-AMP responsive element (CRE), have been implicated in the complex regulation of the TH gene. TH is also known to be upregulated by the glia maturation factor (GMF), a Cdc 10/SWI6 motif-containing protein called V-1, and a variety of additional compounds.

Specifications

Catalog number
ET1612-65
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Dystonia 14 antibody DYT14 antibody DYT5b antibody EC 1.14.16.2 antibody OTTHUMP00000011225 antibody OTTHUMP00000011226 antibody ple antibody Protein Pale antibody TH antibody The antibody TY3H_HUMAN antibody TYH antibody Tyrosine 3 hydroxylase antibody Tyrosine 3 monooxygenase antibody Tyrosine 3-hydroxylase antibody Tyrosine 3-monooxygenase antibody Tyrosine hydroxylase antibody
Abbreviation
TH
Swiss Prot
P07101 Human, P24529 Mouse, P04177 Rat
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human Tyrosine Hydroxylase aa 51-100 / 528.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Tissue
Positive Control
Mouse brain tissue lysate, Rat brain tissue lysate, mouse brain tissue, rat brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:50,000 ;IHC-P: 1:2,000 ;IF-Tissue: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 59 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Tyrosine Hydroxylase Recombinant Rabbit Monoclonal Antibody [SD080-02]?

The catalog number for Tyrosine Hydroxylase Recombinant Rabbit Monoclonal Antibody [SD080-02] is ET1612-65.

What sizes are available for Tyrosine Hydroxylase Recombinant Rabbit Monoclonal Antibody [SD080-02]?

Tyrosine Hydroxylase Recombinant Rabbit Monoclonal Antibody [SD080-02] is available in the following size(s): 100 µL.

Is Tyrosine Hydroxylase Recombinant Rabbit Monoclonal Antibody [SD080-02] in stock?

Tyrosine Hydroxylase Recombinant Rabbit Monoclonal Antibody [SD080-02] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Tyrosine Hydroxylase Recombinant Rabbit Monoclonal Antibody [SD080-02] used for?

The enzyme tyrosine hydroxylase (TH), also designated tyrosine 3-monooxygenase (TY3H), catalyzes the conversion of tyrosine to L-dopa, which is the rate limiting step in the biosynthesis of catecholamines such as dopamine, adrenalin and noradrenalin. TH is thought to play a role in the pathogenesis

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

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