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Product details

HDAC10 Recombinant Rabbit Monoclonal Antibody [SD08-11]

Catalog number ET1612-69

Price for ET1612-69

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Size / count 100 µL

About this product

Histone deacetylases (HDACs) play an important role in the modification of chromatin structure and thus in the suppression and activation of transcription and cellular differentiation. There are 11 members in the HDAC family that are divided into four classes. Class I HDACs represent homologs of the yeast histone deacetylase Rpd3, class II HDACs share strong homology with the yeast histone deacetylase Hda1, class III HDACs are closely related to the yeast Sir2 protein and class IV HDACs comprise histone deacetylase 11 (HDAC11)-related enzymes. HDAC10, also known as HD10, is a member of the class II HDACs. It contains an N-terminal Hda1p-related catalytic domain and a unique C-terminal leucine-rich domain. HDAC10 is ubiquitously expressed and can shuttle between the cytoplasm and nucleus in response to celllular signals. It is able to repress transcription and, like other class II HDAC members, its enzymatic activity is inhibited by Trichostatin A (TSA).

Specifications

Catalog number
ET1612-69
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
DKFZP761B039 antibody HD 10 antibody HD10 antibody HDA10_HUMAN antibody HDAC 10 antibody Hdac10 antibody Histone deacetylase 10 antibody MGC149722 antibody OTTHUMP00000028555 antibody
Abbreviation
HD10
Swiss Prot
Q969S8 Human, Q6P3E7 Mouse, Q569C4 Rat
Cellular Locus
Cytoplasm, Nucleus.
Host
Rabbit
Species Reactivity
Human, Rat, Mouse
Immunogen
Synthetic peptide within Human HDAC10 aa 339-388 / 669.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IP
Positive Control
Rat brain tissue lysate, rat cerebellum tissue lysate, rat pancreas tissue lysate, Hela, A431, A549, human placenta tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IF-Cell: 1:50-1:200 ;IHC-P:1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 71 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for HDAC10 Recombinant Rabbit Monoclonal Antibody [SD08-11]?

The catalog number for HDAC10 Recombinant Rabbit Monoclonal Antibody [SD08-11] is ET1612-69.

What sizes are available for HDAC10 Recombinant Rabbit Monoclonal Antibody [SD08-11]?

HDAC10 Recombinant Rabbit Monoclonal Antibody [SD08-11] is available in the following size(s): 100 µL.

Is HDAC10 Recombinant Rabbit Monoclonal Antibody [SD08-11] in stock?

HDAC10 Recombinant Rabbit Monoclonal Antibody [SD08-11] is currently made to order / not held in immediate stock. Contact us for lead time.

What is HDAC10 Recombinant Rabbit Monoclonal Antibody [SD08-11] used for?

Histone deacetylases (HDACs) play an important role in the modification of chromatin structure and thus in the suppression and activation of transcription and cellular differentiation. There are 11 members in the HDAC family that are divided into four classes. Class I HDACs represent homologs of the

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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