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![Phospho-Raf1 (S43) Recombinant Rabbit Monoclonal Antibody [SD087-05] — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c8c061270361ea81cc2/imageurl/et1612-75.webp)
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Product details
Catalog number ET1612-75
Price for ET1612-75
Size / count 100 µL
Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways. These include ERK/MAP kinases, ribosomal S6 kinase (Rsk)and Raf-1. Raf-1 is a cytoplasmic protein with intrinsic serine/threonine activity. It is broadly expressed in nearly all cell lines tested to date and is the cellular homolog of v-Raf, the product of the transforming gene of the 3611 strain of murine sarcoma virus. The unregulated kinase activity of the v-Raf protein has been associated with transformation and mitogenesis while the activity of Raf-1 is normally suppressed by a regulatory N-terminal domain. Raf-1 is activated in response to activation of a variety of tyrosine kinase receptors as well as in response to pp60v-Src expression. There is accumulating evidence that Ras p21 may play a role in activation of Raf-1 and may play the role of the messenger from membrane tyrosine kinases to Raf-1.
The catalog number for Phospho-Raf1 (S43) Recombinant Rabbit Monoclonal Antibody [SD087-05] is ET1612-75.
Phospho-Raf1 (S43) Recombinant Rabbit Monoclonal Antibody [SD087-05] is available in the following size(s): 100 µL.
Phospho-Raf1 (S43) Recombinant Rabbit Monoclonal Antibody [SD087-05] is currently made to order / not held in immediate stock. Contact us for lead time.
Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways. These include ERK/MAP kinases, ribosomal S6 kinase (Rsk)and Raf-1. Raf-1 is a cytoplasmic protein with intrinsic serine/threonine activity. It is broadly expressed in nearly all cell lines
No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.
Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.
The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.
