CDC40 Recombinant Rabbit Monoclonal Antibody [SD085-9]

About this product

Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins. The cell division control (Cdc) genes are required at various points in the cell cycle. Cdc40, also known as pre-mRNA-processing factor 17 (PRPF17) or EH-binding protein 3 (EHB3), is a 579 amino acid nuclear protein. Cdc40 is essential for the catalytic step II of the pre-mRNA splicing process, in which Cdc40 associates with the spliceosome C complex. Cdc40 contains seven WD repeats, which are important in protein-protein interactions. Cdc40 has sequence similarity to the yeast protein Prp17, which is involved in pre-mRNA splicing and cell cycle progression. The sequence similarity between the mammalian Cdc40 and the yeast Prp17 may indicate an additional role in cell cycle progression for mammalian Cdc40.

Specifications

Catalog number

ET1612-85

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Cdc40 antibody Cell division cycle 40 antibody Cell division cycle 40 homolog antibody EH binding protein 3 antibody EH-binding protein 3 antibody Ehb3 antibody hPRP17 antibody Pre mRNA processing factor 17 antibody Pre mRNA splicing factor 17 antibody Pre-mRNA-processing factor 17 antibody PRP17 antibody PRP17 homolog antibody PRP17_HUMAN antibody PRPF17 antibody

Abbreviation

Ehb3, hPRP17

Swiss Prot

O60508 Human, Q9DC48 Mouse,

Cellular Locus

Nucleus, Nucleus speckle.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human CDC40 aa 41-90 / 579.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC

Positive Control

Hela cells lysates, Hela, HUVEC, SHG-44, rat brain tissue, mouse colon tissue, mouse brain tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:5,000;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 66 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes