Hsp105 Recombinant Rabbit Monoclonal Antibody [SD85-06]

About this product

The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent poly-peptide chains across cellular membranes and regulation of protein folding. Heat shock proteins (also known as molecular chaperones) fall into six general families: HSP 90, HSP 70, HSP 60, the low molecular weight HSPs, the immunophilins and the HSP 110 family. The HSP 110 family (also known as the HSP 105 family) is composed of HSP 105, Apg-1 and Apg-2. HSP 105 is a testis-specific and HSP 90-related protein. Research indicates that HSP 105 is specifically localized in the germ cells and may translocate into the nucleus after heat shock. It is suggested that HSP 105 may contribute to the stabilization of p53 proteins in the cytoplasm of the germ cells, preventing the potential induction of apoptosis by p53.

Specifications

Catalog number

ET1612-88

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Antigen NY CO 25 antibody Antigen NY-CO-25 antibody DKFZp686M05240 antibody Heat shock 105kD alpha antibody Heat shock 105kD antibody Heat shock 105kD beta antibody Heat shock 105kDa protein 1 antibody Heat shock 105kDa protein antibody Heat shock 105kDa/110kDa protein 1 antibody Heat shock 110 kDa protein antibody Heat shock 110kDa protein antibody Heat shock protein 105 kDa antibody HS105_HUMAN antibody HSP105 antibody HSP105A antibody HSP105B antibody HSP110 antibody HSPH 1 antibody Hsph1 antibody KIAA0201 antibody NY CO 25 antibody

Abbreviation

HSPH1, HSP105, HSP110, KIAA0201

Swiss Prot

Q92598 Human, Q61699 Mouse, Q66HA8 Rat

Cellular Locus

Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Rat, Mouse

Immunogen

Recombinant protein within Human Hsp105 aa 17-117 / 858.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, IP

Positive Control

MCF-7 cell lysate, Hela cell lysate, Daudi cell lysate, Hela, HepG2, PANC-1, human liver carcinoma tissue, rat testis tissue, human colon carcinoma tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200;IHC-P: 1:50-1:200;IP: Use at an assay dependent concentration.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 97 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes