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Product details

14-3-3 gamma Recombinant Rabbit Monoclonal Antibody [SD20-65]

Catalog number ET1612-9

Price for ET1612-9

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Size / count 100 µL

About this product

14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 b, g, e, z, h, q and s. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins; by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity, and facilitation of protein modification. Loss of expression contributes to a vast array of pathogenic cellular activities.

Specifications

Catalog number
ET1612-9
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
14 3 3 gamma antibody 14 3 3 protein gamma antibody 14 3 3 protein gamma subtype antibody 14 3 3gamma antibody 14-3-3 protein gamma antibody 1433G_HUMAN antibody 3 monooxygenase/tryptophan 5 monooxgenase activation protein gamma polypeptide antibody KCIP 1 antibody KCIP-1 antibody KCIP1 antibody N-terminally processed antibody Protein kinase C inhibitor protein 1 antibody Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein gamma polypeptide antibody Ywhag antibody
Abbreviation
KCIP-1, YWHAG
Swiss Prot
P61981 Human, P61982 Mouse, P61983 Rat
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human 14-3-3 gamma aa 131-180 / 247.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, FC, IHC-P
Positive Control
293T cell lysate, K562 cell lysate, A431 cell lysate, Hela cell lysate, K562, human breast cancer tissue, human lung cancer tissue, human ovary cancer tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;FC: 1:10-1:50 ;IHC-P: 1:20-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 28 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for 14-3-3 gamma Recombinant Rabbit Monoclonal Antibody [SD20-65]?

The catalog number for 14-3-3 gamma Recombinant Rabbit Monoclonal Antibody [SD20-65] is ET1612-9.

What sizes are available for 14-3-3 gamma Recombinant Rabbit Monoclonal Antibody [SD20-65]?

14-3-3 gamma Recombinant Rabbit Monoclonal Antibody [SD20-65] is available in the following size(s): 100 µL.

Is 14-3-3 gamma Recombinant Rabbit Monoclonal Antibody [SD20-65] in stock?

14-3-3 gamma Recombinant Rabbit Monoclonal Antibody [SD20-65] is currently made to order / not held in immediate stock. Contact us for lead time.

What is 14-3-3 gamma Recombinant Rabbit Monoclonal Antibody [SD20-65] used for?

14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 b, g, e, z, h, q and s. 14-3-3 proteins form dimers that present two binding

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

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