JunD Recombinant Rabbit Monoclonal Antibody [SD0830] — image 1 of 2

Product details

JunD Recombinant Rabbit Monoclonal Antibody [SD0830]

Catalog number ET1612-92

Price for ET1612-92

Size / count 100 µL

About this product

Transcription factor JunD is a protein that in humans is encoded by the JUND gene. The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage results in the production of different isoforms. The dominant negative mutant variant of JunD, known as ΔJunD or Delta JunD, is a potent antagonist of the ΔFosB transcript, as well as other forms of AP-1-mediated transcriptional activity. In the nucleus accumbens, ΔJunD directly opposes many of the neurological changes that occur in addiction (i.e., those induced by ΔFosB). ΔFosB inhibitors (drugs that oppose its action) may be an effective treatment for addiction and addictive disorders. Being an unnatural genetic variant, deltaJunD has not been observed in humans. JunD has been shown to interact with ATF3, MEN1, DNA damage-inducible transcript 3 and BRCA1.

Specifications

Catalog number: ET1612-92
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Activator protein 1 antibody AP 1 antibody AP1 antibody Jun D antibody jun D proto oncogene antibody Jund antibody JunD FL isoform antibody JUND_HUMAN antibody Transcription factor jun D antibody Transcription factor jun-D antibody
Abbreviation: JUND
Swiss Prot: P17535 Human
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within Human JunD aa 101-200 / 347.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IP, IHC-P
Positive Control: HeLa cell lysate, K-562 cell lysate, HeLa, human breast tissue, human breast cancer tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000 ;IF-Cell: 1:100 ;IF-Tissue: 1:50-1:200 ;IP: Use at an assay dependent concentration. ;IHC-P: 1:500
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 35 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for JunD Recombinant Rabbit Monoclonal Antibody [SD0830]?

The catalog number for JunD Recombinant Rabbit Monoclonal Antibody [SD0830] is ET1612-92.

What sizes are available for JunD Recombinant Rabbit Monoclonal Antibody [SD0830]?

JunD Recombinant Rabbit Monoclonal Antibody [SD0830] is available in the following size(s): 100 µL.

Is JunD Recombinant Rabbit Monoclonal Antibody [SD0830] in stock?

JunD Recombinant Rabbit Monoclonal Antibody [SD0830] is currently made to order / not held in immediate stock. Contact us for lead time.

What is JunD Recombinant Rabbit Monoclonal Antibody [SD0830] used for?

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.