Sumo 2+3 Recombinant Rabbit Monoclonal Antibody [JJ087-04] — image 1 of 3

Product details

Sumo 2+3 Recombinant Rabbit Monoclonal Antibody [JJ087-04]

Catalog number ET1701-17

Price for ET1701-17

Size / count 100 µL

About this product

The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, SUMO-2 and SUMO-3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1, SUMO-2 and SUMO-3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO-1 utilizes Ubc9 for conjugation to several target proteins, which include IkBa, MDM2, p53, PML and Ran GAP1. SUMO-2 and SUMO-3 contribute to a greater percentage of protein modification than does SUMO-1, and unlike SUMO-1, they can form polymeric chains. In addition, SUMO-3 regulates b-Amyloid generation and may be critical in the onset or progression of Alzheimer's disease.

Specifications

Catalog number: ET1701-17
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: HSMT3 antibody MGC117191 antibody OTTHUMP00000115275 antibody OTTHUMP00000115276 antibody OTTHUMP00000115277 antibody Sentrin 2 antibody Small ubiquitin like modifier 2 antibody Small ubiquitin related modifier 2 antibody small ubiquitin-like modifier 3 antibody small ubiquitin-related modifier 3 antibody SMT3 homolog 1 antibody SMT3 homolog 2 antibody SMT3 suppressor of mif two 3 homolog 1 antibody SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) antibody SMT3 suppressor of mif two 3 homolog 2 antibody SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) antibody SMT3 suppressor of mif two 3 homolog 3 antibody SMT3A antibody SMT3B antibody SMT3H1 antibody SMT3H2 antibody Sumo2 antibody Sumo3 antibody Ubiquitin like protein SMT3A antibody Ubiquitin like protein SMT3B antibody
Abbreviation: SUMO-2, Smt3B, SUMO2, SUMO-3, Smt3A, SUMO3
Swiss Prot: P55854 Human, P61956 Human, P61957 Mouse, Q9Z172 Mouse, P61959 Rat, Q5XIF4 Rat
Cellular Locus: Cytoplasm, Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human Sumo 3 aa 11-60 / 103.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P
Positive Control: HeLa cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, Human lung tissue lysate, Mouse kidney tissue lysate, HeLa, NIH/3T3, human kidney tissue, mouse kidney tissue, rat kidney tissue, mouse large intestine tissue, rat skin tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 12 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Sumo 2+3 Recombinant Rabbit Monoclonal Antibody [JJ087-04]?

The catalog number for Sumo 2+3 Recombinant Rabbit Monoclonal Antibody [JJ087-04] is ET1701-17.

What sizes are available for Sumo 2+3 Recombinant Rabbit Monoclonal Antibody [JJ087-04]?

Sumo 2+3 Recombinant Rabbit Monoclonal Antibody [JJ087-04] is available in the following size(s): 100 µL.

Is Sumo 2+3 Recombinant Rabbit Monoclonal Antibody [JJ087-04] in stock?

Sumo 2+3 Recombinant Rabbit Monoclonal Antibody [JJ087-04] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Sumo 2+3 Recombinant Rabbit Monoclonal Antibody [JJ087-04] used for?

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.